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NCT05745805
Cohort Follow-up of Epidemic and Neuroimaging for Patients During the 1st Wave of the COVID-19 in China
trial testing Simultaneous cortico-spinal magnetic resonance imaging, Serum in COVID-19 in 600 participants. Currently enrolling.
12 June 2026
Quick facts
| Lead sponsor | First Affiliated Hospital Xi'an Jiaotong University |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 600 |
| Start date | 12 January 2023 |
| Primary completion | 12 June 2026 |
| Estimated completion | 12 September 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Simultaneous cortico-spinal magnetic resonance imaging, Serum
Conditions studied
- COVID-19 — all drugs for COVID-19 →
- Post-COVID-19 Syndrome — all drugs for Post-COVID-19 Syndrome →
- Acute COVID-19 — all drugs for Acute COVID-19 →
- Post-Acute COVID-19 — all drugs for Post-Acute COVID-19 →
Sponsor
First Affiliated Hospital Xi'an Jiaotong University
Who can join
Adults 18 to 65, any sex, with COVID-19 or Post-COVID-19 Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Our main objective is to analyze the development of physical impact, mental health and blood profile over follow-up time during the 1st wave of the COVID-19. Besides, we aim to establish a database of post-COVID-19 based on simultaneous cortico-spinal magnetic resonance imaging data to identify high-risk patients with long COVID and prevent the neurological symptoms evolution, optimize the tactics of management in China.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Multicentre, multitime, multidimension, prospective follow-up cohort study on patients during the first wave of COVID-19 in China: a study protocol.
Wu S, Luo Z, Liu H, Zhu J, et al · · 2025 · cited 1× · PMID 39843379 · DOI 10.1136/bmjopen-2023-083023 -
Acute inflammation and fronto-striatal connectivity in the transition from acute to persistent fatigue after mild COVID-19: A longitudinal fMRI study.
Zhu Q, Lu T, Yuan H, Zhu Y, et al · · 2026 · PMID 41737723 · DOI 10.1016/j.bbih.2026.101196 -
Segregation and integration of resting-state brain networks in a longitudinal long COVID cohort.
Zhang Y, Ye G, Zeng W, Zhu R, et al · · 2025 · PMID 40230529 · DOI 10.1016/j.isci.2025.112237
Verify or expand the search:
- PubMed search for NCT05745805
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other First Affiliated Hospital Xi'an Jiaotong University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05745805 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by First Affiliated Hospital Xi'an Jiaotong University
- Last refreshed: 27 February 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05745805.
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