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NCT05745805

Cohort Follow-up of Epidemic and Neuroimaging for Patients During the 1st Wave of the COVID-19 in China

Recruiting now Last updated 27 February 2023
What this trial tests

trial testing Simultaneous cortico-spinal magnetic resonance imaging, Serum in COVID-19 in 600 participants. Currently enrolling.

Timeline
12 January 2023
Primary endpoint
12 June 2026
12 September 2026

Quick facts

Lead sponsorFirst Affiliated Hospital Xi'an Jiaotong University
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment600
Start date12 January 2023
Primary completion12 June 2026
Estimated completion12 September 2026
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

First Affiliated Hospital Xi'an Jiaotong University

Who can join

Adults 18 to 65, any sex, with COVID-19 or Post-COVID-19 Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Our main objective is to analyze the development of physical impact, mental health and blood profile over follow-up time during the 1st wave of the COVID-19. Besides, we aim to establish a database of post-COVID-19 based on simultaneous cortico-spinal magnetic resonance imaging data to identify high-risk patients with long COVID and prevent the neurological symptoms evolution, optimize the tactics of management in China.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Multicentre, multitime, multidimension, prospective follow-up cohort study on patients during the first wave of COVID-19 in China: a study protocol.
    Wu S, Luo Z, Liu H, Zhu J, et al · · 2025 · cited 1× · PMID 39843379 · DOI 10.1136/bmjopen-2023-083023
  2. Acute inflammation and fronto-striatal connectivity in the transition from acute to persistent fatigue after mild COVID-19: A longitudinal fMRI study.
    Zhu Q, Lu T, Yuan H, Zhu Y, et al · · 2026 · PMID 41737723 · DOI 10.1016/j.bbih.2026.101196
  3. Segregation and integration of resting-state brain networks in a longitudinal long COVID cohort.
    Zhang Y, Ye G, Zeng W, Zhu R, et al · · 2025 · PMID 40230529 · DOI 10.1016/j.isci.2025.112237

Verify or expand the search:

Other trials of Simultaneous cortico-spinal magnetic resonance imaging, Serum

Trials testing the same drug.

Other recruiting trials for COVID-19

Currently open trials in the same condition.

Other First Affiliated Hospital Xi'an Jiaotong University trials

Trials by the same sponsor.

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Data sources for this page

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