NCT05743218: GJZLLCCBGNXJ

Clinical Efficacy of Acupuncture on the Liver Meridian in Women With Diminished Ovarian Reserve

Status unknown NA Last updated 24 February 2023

What this trial tests

NA trial testing electropuncture in Ovarian Reserve in 198 participants. Status unknown.

Timeline

25 January 2023

Primary endpoint
31 December 2023

31 December 2023

Quick facts

Lead sponsor	The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	198
Start date	25 January 2023
Primary completion	31 December 2023
Estimated completion	31 December 2023
Sites	1 location across China

Drugs / interventions tested

• electropuncture

Conditions studied

• Ovarian Reserve — all drugs for Ovarian Reserve →
• Acupuncture Therapy — all drugs for Acupuncture Therapy →
• Meridian — all drugs for Meridian →

Sponsor

The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine

Who can join

Adults 18 to 40, female only, with Ovarian Reserve or Acupuncture Therapy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Diminished ovarian reserve (DOR) refers to a decrease in the number and quality of oocytes in the ovary, which results in impaired ovarian function and decreased fertility. Meanwhile, levels of the anti-Müllerian hormone (AMH), antral follicle count (AFC), and Follicle-Stimulating Hormone (FSH) also decrease in patients with DOR. In general, there is a decline in fertility and premature menopause. Some patients will have low menstrual volume, oligomenorrhea or even amenorrhea, abnormal uterine bleeding, ovulation disorders, infertility and perimenopausal performance before the age of 40, and eventually develop into premature ovarian failure. In recent years, with the changes of social culture, living environment, work pressure and other factors, the incidence of this disease has increased year by year, which has a great impact on women's fertility, mental health, quality of life, family relations and other aspects.

As a green and safe complementary and alternative therapy, acupuncture has been proved to be effective. According to the statistics, 904 (33.54%) of the 2695 syndromes indicated by acupoints of the liver meridian recorded in 93 ancient medical books are reproductive disorders, ranking first in the diseases indicated by the liver meridian and the 14 meridians. The body surface course of the liver meridian is closely related to the genitals, and there is a close relationship between the liver meridian and the genitals in physiology and pathology. According to the theory of the relationship between meridians and zangfu organs, the study aims to verify the efficacy and safety of acupuncture of the liver meridian and provide high-level research evidence for meridian syndrome differentiation of reproductive system diseases via "treatment from the liver."

Publications & conference data

No peer-reviewed publications indexed yet for this trial.