NCT05738746 (MENTAkHEALTH) is a NA clinical trial of Pasteurized Akkermansia muciniphila in Stress, sponsored by Pomeranian Medical University Szczecin.

Who is sponsoring NCT05738746?

NCT05738746 is sponsored by Pomeranian Medical University Szczecin.

What drugs are being tested in NCT05738746?

Interventions in NCT05738746: Pasteurized Akkermansia muciniphila, Placebo.

What condition does NCT05738746 study?

NCT05738746 studies Stress, Healthy, Dietary Supplement.

Is NCT05738746 still recruiting?

NCT05738746 is currently completed. Last updated 18 March 2025.

Last reviewed 2025-03-18 · How we verify

NCT05738746: MENTAkHEALTH

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Efficacy of Pasteurised Akkermansia Muciniphila in Healthy Medical Workers

Completed NA Last updated 18 March 2025

What this trial tests

NA trial testing Pasteurized Akkermansia muciniphila in Stress in 202 participants. Completed in 10 March 2025.

Timeline

24 October 2023

Primary endpoint
10 March 2025

10 March 2025

Quick facts

Lead sponsor	Pomeranian Medical University Szczecin
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	202
Start date	24 October 2023
Primary completion	10 March 2025
Estimated completion	10 March 2025
Sites	2 locations across Poland

Drugs / interventions tested

Pasteurized Akkermansia muciniphila
Placebo

Conditions studied

Stress — all drugs for Stress →
Healthy — all drugs for Healthy →
Dietary Supplement — all drugs for Dietary Supplement →

Sponsor

Pomeranian Medical University Szczecin

Who can join

Adults 18 to 70, any sex, with Stress or Healthy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Gut microbiota alterations secondary to chronic stress might serve as a triggering factor towards manifestation of somatic and mental symptoms. The administration of pasteurised A. muciniphila MucT has the capability of supporting microbiota and improving the gut barrier integrity, which might lead to decrease of inflammation and the negative health consequences of stress in healthy participants.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

A Comprehensive Overview of Postbiotics with a Special Focus on Discovery Techniques and Clinical Applications.
Kumar A, Green KM, Rawat M. · · 2024 · cited 34× · PMID 39335866 · DOI 10.3390/foods13182937
The worldview of <i>Akkermansia muciniphila</i>, a bibliometric analysis.
Zhang Z, Wang J, Dang S, Liu X, et al · · 2025 · cited 2× · PMID 40104597 · DOI 10.3389/fmicb.2025.1500893

Verify or expand the search:

Other recruiting trials for Stress

Currently open trials in the same condition.

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Other Pomeranian Medical University Szczecin trials

Trials by the same sponsor.

NCT07370649 — Long-Acting Cabotegravir and Rilpivirine in People Living With HIV-1 Subtype A6: A Real-World Retrospective Study · not yet recruiting
NCT07328789 — Factors Influencing Cardiac Rehabilitation Success · not yet recruiting
NCT06809101 — Home Monitoring of Complete Blood Count Performed by Patients - a Pilot Study on the Implementation Process in South Bal · recruiting
NCT07070609 — Sagittal Spine Balance in Patients With Chest Wall Deformity · active not recruiting
NCT06743360 — Microanalysis of Changes in 3D Geometry of Orthodontic Mini-implants · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05738746 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Pomeranian Medical University Szczecin
Last refreshed: 18 March 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05738746.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing