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NCT05737667
Advancing mHealth-supported Adoption and Sustainment of an Evidence-based Mental Health Intervention in Sierra Leone
NA trial testing Youth Readiness Intervention (YRI) in Mental Health in 1,454 participants. Participants enrolled and being followed up; not accepting new ones.
31 December 2026
Quick facts
| Lead sponsor | Brown University |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | health services research |
| Enrollment | 1,454 |
| Start date | 15 February 2023 |
| Primary completion | 31 December 2026 |
| Estimated completion | 28 February 2027 |
| Sites | 1 location across Sierra Leone |
Drugs / interventions tested
- Youth Readiness Intervention (YRI)
Conditions studied
- Mental Health — all drugs for Mental Health →
Sponsor
Brown University
Who can join
14 and older, any sex, with Mental Health. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will examine a new implementation strategy for the Youth Readiness Intervention (YRI), an evidence-based mental health intervention. The strategy will (a) leverage a delivery setting (schools) and workforce (teachers) used effectively in low- and middle- income countries; and (b) innovate with technology and mHealth tools to enhance mental health service delivery quality. The YRI will be implemented as an extracurricular resilience-building after school activity in Sierra Leone. Teachers will deliver the YRI and receive either mobile phone-supported supervision or standard in-person supervision. Mobile-based supervision will integrate WhatsApp, a free cross-platform messaging and voice service used widely throughout Africa, with mHealth digital tools. The mHealth tools will support supervision through key features, including voice activated content, fillable forms (i.e., YRI fidelity checklist), and visual dashboards to monitor fidelity. A hybrid type 3 implementation-effectiveness design will allow for evaluation of both mobile phone-based supervision as a new implementation strategy, and clinical effectiveness of the YRI on youth mental and behavioral health as secondary outcomes.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Advancing sustainable implementation of an evidence-based mental health intervention in Sierra Leone's schools: protocol for a hybrid type 3 implementation-effectiveness trial.
Desrosiers A, Carrol B, Ritsema H, Higgins W, et al · · 2024 · cited 1× · PMID 38310232 · DOI 10.1186/s12889-024-17928-w
Verify or expand the search:
- PubMed search for NCT05737667
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Youth Readiness Intervention (YRI)
Trials testing the same drug.
- NCT03542500 — Youth FORWARD Phase 2 YRI and EPP Study · NA · completed
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Other Brown University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05737667 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Brown University
- Last refreshed: 29 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05737667.
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