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NCT05732038
STRIDE: Stress Reduction in Dementia Caregivers
NA trial testing Healthy Minds Program (HMP) in Caregiver Stress in 93 participants. Completed in 3 June 2024.
3 June 2024
Quick facts
| Lead sponsor | Massachusetts General Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 93 |
| Start date | 20 February 2023 |
| Primary completion | 3 June 2024 |
| Estimated completion | 3 June 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Healthy Minds Program (HMP)
- Wellness App (WA)
Conditions studied
- Caregiver Stress — all drugs for Caregiver Stress →
Sponsor
Massachusetts General Hospital
Who can join
18 and older, any sex, with Caregiver Stress. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators aim to conduct a feasibility, proof of concept randomized controlled trial (RCT) of a smartphone app intervention (Healthy Minds Program; HMP) versus Wellness app (WA) among heterogeneous stressed caregivers of individuals with Alzheimer's disease and related dementias (ADRD). The investigators will test its feasibility (primary outcomes) and its preliminary effect in improvement in caregiver stress, emotional distress (depression and anxiety), and mindfulness. Participants will be randomized to one of the two conditions described above
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Mindfulness-Based App to Reduce Stress in Caregivers of Persons With Alzheimer Disease and Related Dementias: Protocol for a Single-Blind Feasibility Proof-of-Concept Randomized Controlled Trial.
Woodworth EC, Briskin EA, Plys E, Macklin E, et al · · 2023 · cited 6× · PMID 37831492 · DOI 10.2196/50108 -
Pilot Randomized Controlled Trial of the Feasibility of a Mobile App-Delivered Mindfulness-Based Intervention for Caregiver Stress.
Plys E, Seward M, Allen EM, Tatar RG, et al · · 2025 · cited 2× · PMID 39921878 · DOI 10.1093/geront/gnaf047
Verify or expand the search:
- PubMed search for NCT05732038
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Caregiver Stress
Currently open trials in the same condition.
- NCT07290387 — Tele-Savvy for Latino Caregivers · NA · recruiting
- NCT07413406 — Comparing Structured Retrieval Practice and Reading-Based Education for Dementia Caregivers · NA · recruiting
- NCT07528261 — ACT Group for Stroke Caregivers · NA · recruiting
- NCT06167746 — iCare4Me Transitions · Phase 3 · recruiting
- NCT05779839 — A Study of Caregiver Connections Via Technology in Dementia · NA · active not recruiting
Other Massachusetts General Hospital trials
Trials by the same sponsor.
- NCT03585946 — Outcomes in Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis · withdrawn
- NCT07214831 — A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerg · NA · not yet recruiting
- NCT06686901 — A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior · NA · not yet recruiting
- NCT05854212 — Behavioral Economics to Implement Nutrition Ranking in Food Pantries · NA · not yet recruiting
- NCT07323446 — The MIND Study: The MGH/MIT Investigation of NAC on Dysregulation · EARLY_PHASE1 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05732038 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Massachusetts General Hospital
- Last refreshed: 21 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05732038.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing