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NCT05730855
Diagnostic Accuracy of lncRNA DQ786243 and miRNA146a in Saliva of Oral Potentially Malignant Lesions
trial testing Real-time Polymerase Chain Reaction technique in Potentially Malignant Lesions in 45 participants. Completed in 23 January 2023.
24 December 2022
Quick facts
| Lead sponsor | Fayoum University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 45 |
| Start date | 1 November 2022 |
| Primary completion | 24 December 2022 |
| Estimated completion | 23 January 2023 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Real-time Polymerase Chain Reaction technique
Conditions studied
- Potentially Malignant Lesions — all drugs for Potentially Malignant Lesions →
- Oral Lichen Planus — all drugs for Oral Lichen Planus →
- Leukoplakia, Oral — all drugs for Leukoplakia, Oral →
Sponsor
Fayoum University
Who can join
Eligibility, any sex, with Potentially Malignant Lesions or Oral Lichen Planus. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to evaluate salivary expression of lncRNA DQ786243 as a potential marker for diagnosis of oral potentially malignant lesions compared to normal controls and its effect on salivary expression of miRNA146a.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Novel insights on oral squamous cell carcinoma management using long non-coding RNAs.
Sur S, Davray D, Basu S, Kheur S, et al · · 2024 · cited 8× · PMID 39308526 · DOI 10.32604/or.2024.052120 -
Long non-coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application.
Tran ET, Patel RA, Chariyamane A, Ray RB. · · 2025 · cited 6× · PMID 40231344 · DOI 10.1002/2211-5463.70042 -
Targeting Regulatory Noncoding RNAs in Human Cancer: The State of the Art in Clinical Trials.
Piergentili R, Sechi S. · · 2025 · cited 2× · PMID 40284466 · DOI 10.3390/pharmaceutics17040471
Verify or expand the search:
- PubMed search for NCT05730855
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05730855 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fayoum University
- Last refreshed: 13 September 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05730855.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing