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NCT05730153
Advanced Platelet-rich Fibrin Combined With Open Debridement in Management of Suprabony Periodontal Defects
Phase 4 trial testing advanced PRF in Periodontitis, Adult in 30 participants. Completed in 26 July 2022.
27 January 2022
Quick facts
| Lead sponsor | October University for Modern Sciences and Arts |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 21 November 2021 |
| Primary completion | 27 January 2022 |
| Estimated completion | 26 July 2022 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- advanced PRF — full drug profile →
Conditions studied
- Periodontitis, Adult — all drugs for Periodontitis, Adult →
Sponsor
October University for Modern Sciences and Arts
Who can join
Adults 18 to 60, any sex, with Periodontitis, Adult. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
in this clinical trial, patients with periodontal defects will be treated with advanced platelet-rich fibrin in conjunction with open debridement
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Single-flap approach versus without concentrate growth factor in the treatment of periodontal supra-osseous defects: A randomized controlled clinical trial.
El-Wakeel N, Mohamed Abd-Elaziz L. · · 2024 · cited 1× · PMID 38419996 · DOI 10.1016/j.sdentj.2023.11.015
Verify or expand the search:
- PubMed search for NCT05730153
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Other October University for Modern Sciences and Arts trials
Trials by the same sponsor.
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- NCT07382245 — Efficacy of Silver Diamine Fluoride Versus Nano-Silver Fluoride in Arresting Active Dentin Caries in Primary Teeth in Yo · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05730153 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by October University for Modern Sciences and Arts
- Last refreshed: 27 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05730153.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing