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NCT05728788

Correlation Between Myocardial Injury and Intestinal Flora Changes Associated With Oncology Drug Therapy

Status unknown Last updated 3 March 2023
What this trial tests

trial testing Antitumor drugs in Cancer Therapy-related Cardiovascular Toxicity in 50 participants. Status unknown.

Timeline
1 July 2022
Primary endpoint
1 June 2023
1 December 2023

Quick facts

Lead sponsorPeking University Third Hospital
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment50
Start date1 July 2022
Primary completion1 June 2023
Estimated completion1 December 2023
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Peking University Third Hospital

Who can join

Adults 18 to 75, any sex, with Cancer Therapy-related Cardiovascular Toxicity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study was to explore the relationship between early myocardial injury caused by tumor drug therapy and intestinal microbial structure changes by echocardiographic two-dimensional speckle tracking technique and intestinal microflora structure detection.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Changes in Intestinal Flora and Serum Metabolites Pre- and Post-Antitumor Drug Therapy in Patients with Non-Small Cell Lung Cancer.
    Tian Z, Liu Y, Zhu D, Cao B, et al · · 2024 · cited 2× · PMID 38256661 · DOI 10.3390/jcm13020529

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Other Peking University Third Hospital trials

Trials by the same sponsor.

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