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NCT05723068: HDV Describe
Burden of Hepatitis D Virus (HDV) Infection in Italy
trial in Chronic Hepatitis D in 515 participants. Completed in 31 December 2024.
30 June 2024
Quick facts
| Lead sponsor | University of Turin, Italy |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 515 |
| Start date | 24 August 2022 |
| Primary completion | 30 June 2024 |
| Estimated completion | 31 December 2024 |
| Sites | 36 locations across Italy |
Conditions studied
- Chronic Hepatitis D — all drugs for Chronic Hepatitis D →
Sponsor
University of Turin, Italy
Who can join
18 and older, any sex, with Chronic Hepatitis D. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The circulation of the Hepatitis D Virus (HDV) has considerably diminished in Italy, secondary to the control of the Hepatitis B Virus (HBV) with vaccination; this has led to the perception that HDV is vanishing and has reduced attention to the diagnosis of Hepatitis D. However, migratory fluxes from HDV endemic areas, fostered by labour-forces globalization, are increasingly reconstituting the reservoir of HDV in the country and hepatitis D has not yet vanished in native Italians but will remain an important medical issue for several years to come. As the epidemiologic and clinical features of HDV infection in migrant communities are largely unknown and the features of native Italians with long standing HDV infections have not been updated, this project intends to establish the contemporary epidemiological and medical context of HDV in immigrants in Italy and to determine the clinical characteristics and needs of the residual cohort of native HDV Italians, through the analysis of all HDV cases recruited in 12 months in a coordinated network of 35 Italian medical centers. The data will provide an appraisal of the burden of hepatitis D in the country and of its impact on the National Health System. They will present the paradigm of the current trend of HDV infection in high-income countries in the world.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Medical Impact of Hepatitis D Virus Infection in Natives and Immigrants: The Italian Paradigm.
Caviglia GP, Dileo E, Olivero A, Mengozzi G, et al · · 2025 · cited 2× · PMID 40729522 · DOI 10.1111/liv.70242
Verify or expand the search:
- PubMed search for NCT05723068
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Chronic Hepatitis D
Currently open trials in the same condition.
- NCT07454837 — Phase 2b/3 Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide · Phase 2, PHASE3 · recruiting
Other University of Turin, Italy trials
Trials by the same sponsor.
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- NCT07311291 — The Effect of Different Hemostatic Agents on Hemorrhage Control, Pain and Quality of Life After Endodontic Microsurgery. · NA · completed
- NCT06904963 — Efficacy of Oral Hygiene Instructions Carried Out Using an Intra-oral Scanner · NA · completed
- NCT07047261 — Efficacy of a Xanthan-based Chlorhexidine Gel in the Treatment of Peri-implant Mucositis · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05723068 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Turin, Italy
- Last refreshed: 5 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05723068.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing