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NCT05722613

Diagnostic Potential of the Salivary Biomarkers to Differentiate Statuses of Periodontitis

Status unknown Last updated 10 February 2023
What this trial tests

trial in Periodontitis in 120 participants. Status unknown.

Timeline
1 May 2022
Primary endpoint
1 April 2023
1 June 2023

Quick facts

Lead sponsorUniversity of Baghdad
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment120
Start date1 May 2022
Primary completion1 April 2023
Estimated completion1 June 2023
Sites1 location across Iraq

Conditions studied

Sponsor

University of Baghdad

Who can join

Adults 18 to 85, any sex, with Periodontitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Periodontitis is a chronic inflammatory disease characterized by both dysbiosis of oral microbiota and proinflammatory events involving both cells and mediators from innate and adaptive immunity. These events lead to chronic inflammation of periodontal soft and hard tissues sharing many features with other chronic inflammatory diseases. These events lead to chronic inflammation of periodontal soft and hard tissues sharing many features with other chronic inflammatory diseases. Chronic inflammation is driven by various mediators, of which a significant part is attributed to the interactions within cytokine networks. While proinflammatory cytokines, including interleukin (IL) -1α, IL-1β, TNF-α, IL-6, and IL-17, contribute to acute and chronic inflammation and tissue injury, a second group with antagonist effects is formed by cytokines such as IL-10

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Diagnostic Potential of Salivary Interleukin-1<i>β</i> and IL-10 for Distinguishing Periodontal Health From Periodontitis and Stable From Unstable Periodontitis: A Case-Control Study.
    Raheem ZJ, Abdulbaqi HR. · · 2024 · cited 4× · PMID 39445112 · DOI 10.1155/2024/8006278

Verify or expand the search:

Other recruiting trials for Periodontitis

Currently open trials in the same condition.

Other University of Baghdad trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05722613.

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