NCT05720741 is a NA clinical trial of Project THINK in Anxiety, sponsored by Harvard University.

Who is sponsoring NCT05720741?

NCT05720741 is sponsored by Harvard University.

What drugs are being tested in NCT05720741?

Interventions in NCT05720741: Project THINK, Project SHARE.

What condition does NCT05720741 study?

NCT05720741 studies Anxiety, Depression, Stress.

Is NCT05720741 still recruiting?

NCT05720741 is currently completed. Last updated 28 February 2024.

Last reviewed 2024-02-28 · How we verify

NCT05720741

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Project THINK: Trial of a Brief Cognitive Restructuring Intervention

Completed NA Last updated 28 February 2024

What this trial tests

NA trial testing Project THINK in Anxiety in 597 participants. Completed in 1 February 2024.

Timeline

1 March 2023

Primary endpoint
15 November 2023

1 February 2024

Quick facts

Lead sponsor	Harvard University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	597
Start date	1 March 2023
Primary completion	15 November 2023
Estimated completion	1 February 2024
Sites	1 location across United States

Drugs / interventions tested

Project THINK
Project SHARE

Conditions studied

Anxiety — all drugs for Anxiety →
Depression — all drugs for Depression →
Stress — all drugs for Stress →

Sponsor

Harvard University

Who can join

Adults 10 to 16, any sex, with Anxiety or Depression. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This project will involve testing a brief (\~30 minute) digital intervention aimed at teaching youth the evidence-based strategy of changing unhelpful thoughts (i.e., cognitive restructuring). The investigators will test the intervention's efficacy compared to an active control condition. Participants (students in grades 5-10 in U.S. schools) will be asked to complete measures of mental health and well-being prior to the intervention as well as 1, 3, and 6-months after the intervention. If the intervention is found to be effective, its brevity and scalability would make it an invaluable resource for supplementing traditional psychotherapy and potentially preventing the onset of mental illness requiring specialized intensive care.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Anxiety

Currently open trials in the same condition.

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NCT07473505 — Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospect · recruiting

Other Harvard University trials

Trials by the same sponsor.

NCT07316647 — Using Conversational AI to Teach Growth Mindset Skills to Youths in India · NA · completed
NCT06114862 — Brief Interventions on Social Media to Reduce Suicide Risk (Intervention 2) · NA · withdrawn
NCT07394465 — First Tones: Artistic Communal Practices for 4 and 5 Year Old Children · NA · completed
NCT06217705 — Testing the Effects of Project Calm in Ukrainian Schools · NA · completed
NCT06114875 — Brief Interventions on Social Media to Reduce Suicide Risk (Intervention 1) · NA · terminated

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05720741 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Harvard University
Last refreshed: 28 February 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05720741.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing