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NCT05719792
Comparison of the Effectiveness of Erector Spina Plane Block and Transforaminal Anterior Epidural Injections
trial testing Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation in 50 participants. Status unknown.
1 June 2023
Quick facts
| Lead sponsor | Marmara University |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 1 November 2022 |
| Primary completion | 1 June 2023 |
| Estimated completion | 1 August 2023 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Transforaminal Epidural Steroid Injection — full drug profile →
- Erector Spina Plane Block
Conditions studied
- Lumbar Disc Herniation — all drugs for Lumbar Disc Herniation →
- Radiculopathy Lumbar — all drugs for Radiculopathy Lumbar →
Sponsor
Marmara University
Who can join
Adults 18 to 65, any sex, with Lumbar Disc Herniation or Radiculopathy Lumbar. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Low back pain is one of the leading causes of disability and its social burden and economic cost are quite high. The lifetime prevalence in the population is frequently reported between 40% and 70%. Although there are many reasons that can lead to low back pain, radicular pain, which develops mostly secondary to lumbar disc hernia, is one of the most common pathologies. Epidural corticosteroid and local anesthetic injections are an important treatment option in the treatment of lumbar radicular pain that does not respond to conservative methods. epidural injections; includes transforaminal, interlaminar and caudal approaches. The advantage of the transforaminal approach is that it allows access to the anterior epidural area, which is the region of pathology, and that it can spread to the target specifically around the inflamed nerve roots. The standard imaging technology used for steroid injections with this approach is fluoroscopy. However, the aforementioned approaches carry the risk of dural puncture, epidural hematoma, epidural abscess, nerve damage, paralysis and many complications. In addition, radiation exposure is another problem. It may be possible to avoid a significant part of these risks by applying interfacial blocks used in regional anesthesia and postoperative pain control in the lumbar region. Recently, Erector Spina Plan Block (ESPB), an interfascial block technique, has been frequently applied under ultrasound (US) guidance as an alternative method to conventional paravertebral block. Investigators also frequently refer to this procedure in the clinic for patients with lumbar radicular pain. In the literature, there are case reports of lumbar ESPB applied to patients with radicular pain due to disc herniation. Beyond case-level reports, there is no clinical study investigating the efficacy of this procedure technique for applications in the lumbar region. Starting from here, the aim of this study is; Investigators determined to compare the efficacy of erector spina plane block and transforaminal anterior epidural steroid injections in patients with radicular pain due to lumbar disc herniation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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Related trials
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Trials testing the same drug.
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Other Marmara University trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05719792 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Marmara University
- Last refreshed: 9 February 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05719792.
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