Last reviewed · How we verify
NCT05719259: POS-VAP
Perpetual Observational Study - Ventilator Associated Pneumonia
trial in Ventilator Associated Pneumonia in 20,000 participants. Currently enrolling.
1 December 2025
Quick facts
| Lead sponsor | European Clinical Research Alliance for Infectious Diseases (ECRAID) |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 20,000 |
| Start date | 3 August 2022 |
| Primary completion | 1 December 2025 |
| Estimated completion | 1 March 2026 |
| Sites | 35 locations across France, Italy, Netherlands, Greece, Belgium, Serbia, United Kingdom, Germany |
Conditions studied
- Ventilator Associated Pneumonia — all drugs for Ventilator Associated Pneumonia →
Sponsor
European Clinical Research Alliance for Infectious Diseases (ECRAID)
Who can join
18 and older, any sex, with Ventilator Associated Pneumonia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Ventilator-Associated Pneumonia (VAP) is a bacterial respiratory infection that patients in the Intensive Care Unit (ICU) often get when they cannot breathe for themselves and require mechanical ventilation. It is linked to higher chances of death, a longer stay in the hospital, higher costs, and the use of more antibiotics. Options to help prevent or treat this disease are in development and will require evaluation in future clinical trials. The goal of POS-VAP is to build and continuously train a network of ICUs to be prepared for doing these trials, to facilitate their execution.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Perpetual observational study of the clinical and microbiological epidemiology of ventilator-associated pneumonia in Europe.
Jackson H, Hernandez Padilla AC, Vintcent LEM, Barac A, et al · · 2026 · PMID 41821089 · DOI 10.1186/s13054-025-05753-5
Verify or expand the search:
- PubMed search for NCT05719259
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Ventilator Associated Pneumonia
Currently open trials in the same condition.
- NCT07102407 — Effect of a Constructivist Educational Program on Preventing Ventilator-Associated Pneumonia in Intensive Care Units · NA · recruiting
- NCT06554327 — Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens · NA · recruiting
- NCT05591924 — Early Severe Illness TrAnslational BioLogy InformaticS in Humans · recruiting
- NCT06092554 — Probiotics to Actively Counter Ventilator Associated Pneumonia (PROACT) · NA · recruiting
- NCT05979545 — EaRly impAct theraPy With Ceftazidime-avibactam Via rapID Diagnostics · Phase 4 · recruiting
Other European Clinical Research Alliance for Infectious Diseases (ECRAID) trials
Trials by the same sponsor.
- NCT05814237 — POS-ARI-ER Observational Study of Acute Respiratory Infections · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05719259 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by European Clinical Research Alliance for Infectious Diseases (ECRAID)
- Last refreshed: 15 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05719259.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing