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NCT05718752: METALEXO
Characterization of the Plasma Metallomic Profile to Acute Exercise in Healthy Men and Women (METALEXO)
trial testing Maximal incremental exercise test in Healthy Young Men in 38 participants. Completed in 14 April 2024.
14 April 2024
Quick facts
| Lead sponsor | University of Rennes 2 |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 38 |
| Start date | 7 February 2023 |
| Primary completion | 14 April 2024 |
| Estimated completion | 14 April 2024 |
| Sites | 1 location across France |
Drugs / interventions tested
- Maximal incremental exercise test
- 30-min submaximal exercise test
Conditions studied
- Healthy Young Men — all drugs for Healthy Young Men →
- Healthy Young Women — all drugs for Healthy Young Women →
Sponsor
University of Rennes 2
Who can join
Adults 18 to 35, any sex, with Healthy Young Men or Healthy Young Women. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Among the various trace elements playing a key role in physical performance, iron is probably one of the most studied in the last 30 years. Iron is an essential component of both hemoglobin and myoglobin allowing an optimal oxygen delivery to organs, especially to skeletal muscle. Iron also plays a major role in the mitochondrial respiratory chain, as well as in the activity of numerous enzymes. Recent studies support the existence of a strong interaction between the iron metabolism and the other non-ferrous trace elements including among others zinc, copper or cobalt. The latter, but also other trace element metals could thus play an important role in physical performance. The finality of this project is thus 1) to determine the variations of plasma iron and non-ferrous metals in response to an acute exercise, 2) better understand the interactions between all these metals, 3) to determine if such responses to exercise are different or not depending on sex.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05718752
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other University of Rennes 2 trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05718752 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Rennes 2
- Last refreshed: 28 June 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05718752.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing