Last reviewed · How we verify
NCT05718596
Quantitative Assessment of the Efficacy of Sweeps Laser Activation Systems
NA trial testing sweeps laser to use irrigation activation in Periapical Periodontitis in 20 participants. Completed in 10 December 2022.
10 November 2022
Quick facts
| Lead sponsor | Seyda Ersahan, DDS, PhD |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 10 September 2022 |
| Primary completion | 10 November 2022 |
| Estimated completion | 10 December 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- sweeps laser to use irrigation activation
- PUI to use irrigation activation
Conditions studied
- Periapical Periodontitis — all drugs for Periapical Periodontitis →
- Polymerase Chain Reaction — all drugs for Polymerase Chain Reaction →
- Enterococcus Faecalis Infection — all drugs for Enterococcus Faecalis Infection →
Sponsor
Seyda Ersahan, DDS, PhD
Who can join
Adults 18 to 65, any sex, with Periapical Periodontitis or Polymerase Chain Reaction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Aim of the present study was to determine the intraradicular microbiota of previously root canal-treated teeth with apical periodontitis using droplet digital polymerase chain reaction (ddPCR) and to investigate the antibacterial effectiveness of different irrigation activation methods \[ Sweeps laser and PUI group \] that will make classical chemomechanical preparation more effective. This superiority, parallel, randomized clinical trial was conducted in the clinic of the Endodontic Department, Faculty of Dentistry, Istanbul Medipol University, Istanbul. 30 patients with apical periodontitis (one tooth each) were randomly allocated into two groups according to the used (n=15, for each): the Sweeps laser group (A) or the vdw ultra group (B). Total bacterial loads, as well as the amount of Enterococcus faecalis (E.faecalis) were determined before (S1) and after (S2) chemomechanical preparation and finally, after intracanal medication (S3) by means of ddPCR.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05718596
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Periapical Periodontitis
Currently open trials in the same condition.
- NCT07501585 — Hyaluronic Acid in Endodontic Microsurgery · NA · recruiting
- NCT07252258 — Comparison of Frequency of Calcium Hydroxide Mixed With 0.2% Chlorhexidine Versus Saline as Intracanal Medicament in Per · NA · active not recruiting
- NCT07019298 — Success of Endodontic Treatment With Different Obturation Techniques and Sealer Cements · NA · recruiting
- NCT07018284 — Postoperative Pain Evaluation After Obturation With Different Sealers · NA · recruiting
- NCT07026435 — Comparison of LSTR and Pulpectomy in Primary Molars of Pediatric Patients (LSTR-PULP) · NA · active not recruiting
Other Seyda Ersahan, DDS, PhD trials
Trials by the same sponsor.
- NCT05847647 — Evaluation of the Effect of Leukocyte and Platelet-rich Fibrin on Healing After Periradicular Surgery · NA · completed
- NCT05690763 — Quantitative Assessment of the Efficacy of Two Irrigation Activation Systems · NA · completed
- NCT05857436 — Relationship Apical Periodontitis and the Main Bacterial Species in the Oral Microbiota · NA · completed
- NCT04978545 — The Effect of Ca(OH)2 in Apical Periodontitis · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05718596 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Seyda Ersahan, DDS, PhD
- Last refreshed: 6 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05718596.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing