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NCT05718011
Prevention of Shivering After Spinal Anesthesia
Phase 4 trial testing Dexmedetomidine in Postoperative Shivering in 116 participants. Completed in 19 August 2021.
19 August 2021
Quick facts
| Lead sponsor | Pakistan Air Force (PAF) Hospital Islamabad |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 116 |
| Start date | 20 February 2021 |
| Primary completion | 19 August 2021 |
| Estimated completion | 19 August 2021 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Dexmedetomidine (dexmedetomidine) — full drug profile →
- Ketamine (ketamine) — full drug profile →
Conditions studied
- Postoperative Shivering — all drugs for Postoperative Shivering →
Sponsor
Pakistan Air Force (PAF) Hospital Islamabad
Who can join
Adults 20 to 50, any sex, with Postoperative Shivering. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Recently, ketamine and dexmedetomidine have been used to prevent shivering during anaesthesia, with good results. Ketamine (a competitive NMDA receptor antagonist) plays a role in thermoregulation at various levels and ketamine, has been shown to inhibit postoperative shivering in some reports and studies.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05718011
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Dexmedetomidine
Trials testing the same drug.
- NCT06824077 — Reducing Days DELirious With DEXmedetomidine as Part of an Intensive Care Unit Sleep Promotion Bundle · EARLY_PHASE1 · not yet recruiting
- NCT07398066 — DEXmedetomidine for Postoperative Analgesia and Delirium Prevention After NEUROsurgery (DEX-NEURO Trial) · NA · not yet recruiting
- NCT07377981 — An Exploratory Study of the Efficacy and Safety of Esketamine and Dexmedetomidine in Non-Intubated ICU Patients With Hyp · Phase 4 · not yet recruiting
- NCT07306702 — Dexmedetomidine-Enhanced PCIA After Lobectomy in Nicotine-Dependent Patients · Phase 4 · withdrawn
- NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
Other recruiting trials for Postoperative Shivering
Currently open trials in the same condition.
- NCT06843031 — The Role of Perfusion Index in Defining Postoperative Shivering · active not recruiting
Other Pakistan Air Force (PAF) Hospital Islamabad trials
Trials by the same sponsor.
- NCT06962644 — Association of Urinary Tract Infection With Preeclampsia During Pregnancy · recruiting
- NCT06608056 — Comparing Opioids Vs NSAIDs for Postoperative Pain Management in Unilateral Primary Open Inguinal Hernia Repair · NA · completed
- NCT06605235 — The Ideal Local Anesthetic for Intraperitoneal Gallbladder Bed Infiltration Following Laparoscopic Cholecystectomy · NA · completed
- NCT05071794 — Effect of Propofol on Postoperative Nausea and Vomiting. · Phase 4 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05718011 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pakistan Air Force (PAF) Hospital Islamabad
- Last refreshed: 8 February 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05718011.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing