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NCT05716620
Utility of Abbreviated Magnetic Resonance Imaging as a Screening Tool for Hepatocellular Carcinoma in Cirrhotic Patients
trial testing MRI in Hepatocellular Carcinoma in 380 participants. Status unknown.
7 February 2025
Quick facts
| Lead sponsor | Post Graduate Institute of Medical Education and Research, Chandigarh |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 380 |
| Start date | 8 February 2022 |
| Primary completion | 7 February 2025 |
| Estimated completion | 7 February 2025 |
| Sites | 1 location across India |
Drugs / interventions tested
- MRI — full drug profile →
Conditions studied
- Hepatocellular Carcinoma — all drugs for Hepatocellular Carcinoma →
Sponsor
Post Graduate Institute of Medical Education and Research, Chandigarh
Who can join
Adults 40 to 65, any sex, with Hepatocellular Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this study is Utility of abbrevational magnetic resonance imaging as a screening tool for hepatocellular carcinoma in cirrhotic patients. The primary objective of the study is: • HCC detection rate of US vs AMRI in cirrhotic patients The secondary objective of the study are: * False referral rate of US vs AMRI: false referral will be defined as lack of HCC on complete MRI despite a positive US or AMRI. * Positive predictive value of US vs AMRI: The positive predictive value will be defined as the number of patients with true positive results in patients with positive US/AMRI. Participants will be evaluated by two rounds of screening 6 months apart using paired US and non-enhanced AMRI.
Publications & conference data
5 peer-reviewed publications reference this trial (live from Europe PMC):
-
Recent advances and issues in imaging modalities for hepatocellular carcinoma surveillance.
Lee DH. · · 2025 · cited 5× · PMID 40007309 · DOI 10.17998/jlc.2025.02.16 -
Persisting challenges in the early detection of hepatocellular carcinoma.
Arvind A, Redmon K, Singal AG. · · 2025 · cited 3× · PMID 39943795 · DOI 10.1080/14737140.2025.2467184 -
Abbreviated MRI-Based Surveillance Strategies for Early Hepatocellular Carcinoma Detection.
Park HJ, Kim DW, Choi WM, Kim SY. · · 2025 · cited 1× · PMID 40502477 · DOI 10.3348/jksr.2024.0153 -
Noncontrast abbreviated MRI demonstrates superior diagnostic accuracy compared to ultrasound for hepatocellular carcinoma detection: Interim results from a prospective surveillance trial.
Gupta P, Singh S, Gulati A, Mudgil P, et al · · 2026 · PMID 42113186 · DOI 10.1097/hep.0000000000001788 -
How to Design a Study and Write a Grant in Radiology?
Gupta P, Singhal M. · · 2025 · PMID 39802716 · DOI 10.1055/s-0044-1792077
Verify or expand the search:
- PubMed search for NCT05716620
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Hepatocellular Carcinoma
Currently open trials in the same condition.
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Other Post Graduate Institute of Medical Education and Research, Chandigarh trials
Trials by the same sponsor.
- NCT07322237 — DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With Cirrhosis · Phase 4 · recruiting
- NCT07436988 — Affordable Made-in-India Microspheres for Liver Cancer Therapy · Phase 1 · not yet recruiting
- NCT07286643 — Echocardiography-guided Cirrhosis and Liver Failure-Intensive Care Protocol Sepsis · NA · recruiting
- NCT07280390 — Microplastics, Cirrhosis and Portal Hypertension · not yet recruiting
- NCT07182877 — Comparison of Dwell Time of Open Versus Closed Type Peripheral Intravenous Cannula · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05716620 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Post Graduate Institute of Medical Education and Research, Chandigarh
- Last refreshed: 8 February 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05716620.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing