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NCT05716191
Study on the Relationship Between Iodine Nutrition and Thyroid Diseases in the Elderly
trial testing Naturally different iodine levels exposure in Nutrition, Healthy in 1,000 participants. Status unknown.
1 June 2025
Quick facts
| Lead sponsor | Tianjin Medical University |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 1,000 |
| Start date | 17 February 2023 |
| Primary completion | 1 June 2025 |
| Estimated completion | 30 December 2025 |
| Sites | 3 locations across China |
Drugs / interventions tested
- Naturally different iodine levels exposure
Conditions studied
- Nutrition, Healthy — all drugs for Nutrition, Healthy →
- Elderly — all drugs for Elderly →
Sponsor
Tianjin Medical University
Who can join
18 and older, any sex, with Nutrition, Healthy or Elderly. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aging trend of China's population is intensifying. More than 50% of the elderly in China suffer from thyroid disease. Thyroid dysfunction in the elderly increases the risk of cardiovascular and metabolic diseases. Even if thyroid-stimulating hormone (TSH) is within the normal range, brain atrophy and infarction-like vascular damage in elderly males will be aggravated with the increased TSH level. Iodine is an essential component of thyroid hormones. Iodine deficiency or excess may lead to a series of thyroid diseases. The risk threshold of iodine intake in the elderly is unknown. The goal of this observational study is to clarify the relationship between thyroid diseases and iodine intake in the elderly. The aims are: 1. to clarify the differences in the prevalence of thyroid diseases in the elderly with different iodine nutrition backgrounds. 2. to analyze the effects of mild iodine deficiency and iodine excess on the thyroid health of the elderly. 3. to explore the hazard threshold of iodine intake for old people. 4. to compare the differences in thyroid disease and iodine nutritional status between young and middle-aged people and old people.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Iodine Excess Is Associated with Thyroid Dysfunction Among the Elderly.
Jin Q, Wang Z, Li J, Zhang H, et al · · 2025 · PMID 39441230 · DOI 10.1007/s12011-024-04420-0
Verify or expand the search:
- PubMed search for NCT05716191
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05716191 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tianjin Medical University
- Last refreshed: 16 August 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05716191.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing