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NCT05714826: COARC
Comprehensive Optimization At-time of Radical Cystectomy Intervention
NA trial testing Preop Intervention and Monitored Recovery in Bladder Cancer in 194 participants. Currently enrolling.
25 May 2026
Quick facts
| Lead sponsor | University of Texas Southwestern Medical Center |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 194 |
| Start date | 25 April 2024 |
| Primary completion | 25 May 2026 |
| Estimated completion | 24 August 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Preop Intervention and Monitored Recovery
- Usual Care
Conditions studied
- Bladder Cancer — all drugs for Bladder Cancer →
- Radical Cystectomy — all drugs for Radical Cystectomy →
Sponsor
University of Texas Southwestern Medical Center
Who can join
18 and older, any sex, with Bladder Cancer or Radical Cystectomy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The proposed study is aimed at a comprehensive optimization at-time of radical cystectomy (COARC) intervention that focuses on patient optimization throughout the perioperative continuum, from the pre-operative setting to the post-operative period, among patients undergoing radical cystectomy for bladder cancer. This multi-modal strategy will focus on three phases of care around surgery: the pre-operative, peri-operative, and post-operative phases. The intervention group will focus on multiple areas of patient optimization including remote patient monitoring for the earlier identification of potential complications. The overall study mission is to decrease complication rates after radical cystectomy using this comprehensive approach.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05714826
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05714826 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Texas Southwestern Medical Center
- Last refreshed: 2 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05714826.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing