Last reviewed · How we verify
NCT05714397
Effectiveness of Cingal™ for Improving Pain Scores and Function in Anterior Knee Pain
NA trial testing Cingal in Anterior Knee Pain Syndrome in 24 participants. Not yet recruiting.
1 April 2026
Quick facts
| Lead sponsor | Banff Sport Medicine Foundation |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 24 |
| Start date | 1 April 2026 |
| Primary completion | 1 April 2026 |
| Estimated completion | 1 November 2026 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Cingal — full drug profile →
Conditions studied
- Anterior Knee Pain Syndrome — all drugs for Anterior Knee Pain Syndrome →
Sponsor
Banff Sport Medicine Foundation
Who can join
Adults 18 to 35, any sex, with Anterior Knee Pain Syndrome. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
2D Kinematic Data
Time frame: baseline, 6 weeks, 12 weeks
Kinematic data will be collected at baseline and 6 and 12 weeks after administration of the Cingal™ injection. Outcome measures include ankle dorsiflexion at contact, maximum rear foot eversion, knee flexion at contact, knee adduction in late stance, and hip joint angle. In addition, the mean of three angle measurements for each parameter will be recorded.
Sponsor's own description
Anterior Knee Pain (AKP) is a common condition that can be challenging to treat effectively. The main goal of treatment regimens is to improve the function of the knee. However, treatment can be challenging due to the knee pain experience. Cingal™ contains hyaluronic acid (HA), which acts as a joint lubricant, and the corticosteroid triamcinolone hexacetonide (TH). Some studies have shown that Cingal™ can improve joint function and provide short-term pain relief.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05714397
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Cingal
Trials testing the same drug.
- NCT04640961 — Study of Cingal® for Symptomatic Relief of Osteoarthritis of Shoulder Joint · NA · completed
- NCT04640298 — Study of Cingal® for Symptomatic Relief of Osteoarthritis of Hip Joint · NA · completed
- NCT04640974 — Study of Cingal® for Symptomatic Relief of Osteoarthritis of Ankle Joint · NA · completed
- NCT04231318 — Study of Cingal® and Triamcinolone Hexacetonide for the Relief of Knee Osteoarthritis Pain · Phase 3 · completed
- NCT04084704 — A Prospective Evaluation of the Cingal Injection for Hip Osteoarthritis · NA · completed
Other recruiting trials for Anterior Knee Pain Syndrome
Currently open trials in the same condition.
- NCT06832852 — Which Model of Care is the Most Cost-effective in the Treatment of Musculoskeletal Disorders? · NA · recruiting
Other Banff Sport Medicine Foundation trials
Trials by the same sponsor.
- NCT06169800 — Biologic Augment of the Medial Patellofemoral Ligament Following Primary Lateral Patellofemoral Dislocation (BioPPD) · NA · recruiting
- NCT05759039 — SHould You TransFer the Tubercle? · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05714397 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Banff Sport Medicine Foundation
- Last refreshed: 3 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05714397.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing