NCT05708690 is a Phase 4 clinical trial of Tranexamic Acid 100 MG/ML in Coronary Artery Disease, sponsored by Indonesia University.

Who is sponsoring NCT05708690?

NCT05708690 is sponsored by Indonesia University.

What drugs are being tested in NCT05708690?

Interventions in NCT05708690: Tranexamic Acid 100 MG/ML, normal saline.

What condition does NCT05708690 study?

NCT05708690 studies Coronary Artery Disease, Valvular Heart Disease, Surgical Blood Loss.

Is NCT05708690 still recruiting?

NCT05708690 is currently completed. Last updated 1 February 2023.

Last reviewed 2023-02-01 · How we verify

NCT05708690

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Topical Effect of Tranexamic Acid in Postoperative Bleeding and Blood Products Transfusion After Cardiac Surgery

Completed Phase 4 Last updated 1 February 2023

What this trial tests

Phase 4 trial testing Tranexamic Acid 100 MG/ML in Coronary Artery Disease in 132 participants. Completed in 6 January 2023.

Timeline

1 October 2022

Primary endpoint
31 December 2022

6 January 2023

Quick facts

Lead sponsor	Indonesia University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	132
Start date	1 October 2022
Primary completion	31 December 2022
Estimated completion	6 January 2023
Sites	1 location across Indonesia

Drugs / interventions tested

Tranexamic Acid 100 MG/ML — full drug profile →
normal saline

Conditions studied

Coronary Artery Disease — all drugs for Coronary Artery Disease →
Valvular Heart Disease — all drugs for Valvular Heart Disease →
Surgical Blood Loss — all drugs for Surgical Blood Loss →

Sponsor

Indonesia University

Who can join

Adults 18 to 75, any sex, with Coronary Artery Disease or Valvular Heart Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a single-center, double-blind, randomized controlled trial (RCT) comparing two groups of application of topical dose of tranexamic acid (TxA) versus placebo in patients undergoing coronary artery bypass graft (CABG), off pump coronary bypass graft cardiac surgery (OPCAB), and adult heart valve surgery. The primary outcomes of this study comprised of two parameters; post operative bleeding and blood product transfusion. The primary outcomes were assessed during the operation, until 48-hour post operative.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Tranexamic Acid 100 MG/ML

Trials testing the same drug.

NCT06270407 — The Effect of Local Application of Tranexamic Acid Versus Placebo on Postoperative Complications in Plastic Surgery · Phase 4 · recruiting
NCT05919615 — Use of Tranexamic Acid in the Total Knee Arthroplasty. · NA · completed
NCT04192643 — INTERVENTION WITH TRANEXAMIC ACID TO REDUCE HAEMORRHAGE DURING LAPAROSCOPIC MYOMECTOMY · NA · unknown
NCT03934047 — Visual Field Infiltration of Tranexamic Acid Reduced the Blood Loss in Total Knee Arthroplasty · NA · unknown
NCT03690037 — Investigating the Effect of Intravenous and Oral Tranexamic Acid on Blood Loss After Primary Hip and Knee Arthroplasty · Phase 4 · completed

Other recruiting trials for Coronary Artery Disease

Currently open trials in the same condition.

NCT07399002 — LONG NAGOMI™ PMCF STUDY · recruiting
NCT07420582 — Antegrade Autologous Blood Reinfusion After CPB · recruiting
NCT07493603 — A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart Disease · Phase 1, PHASE2 · recruiting
NCT06535568 — Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO · NA · recruiting
NCT07286578 — A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Under · NA · recruiting

Other Indonesia University trials

Trials by the same sponsor.

NCT07137130 — Secretome TGF Beta 3 · NA · not yet recruiting
NCT07420335 — Preoperative Shoulder Exercises and Postoperative Inflammation, Pain, and Function After Modified Radical Mastectomy · NA · not yet recruiting
NCT07278284 — The Effectiveness of Press Needle Acupuncture on Preoperative Anxiety in Tympanoplasty and Mastoidectomy · NA · recruiting
NCT07337187 — Effect of Thread-Embedding Acupuncture at EX-B2 on Pain and Quality of Life in Chronic Low Back Pain · NA · not yet recruiting
NCT07242001 — Laser Acupuncture for Otitis Media With Effusion in Children · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05708690 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Indonesia University
Last refreshed: 1 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05708690.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing