NCT05705596 is a EARLY_PHASE1 clinical trial of Sucrose in Blood Glucose Fluctuations, sponsored by University of Vienna.

Who is sponsoring NCT05705596?

NCT05705596 is sponsored by University of Vienna.

What drugs are being tested in NCT05705596?

Interventions in NCT05705596: Sucrose, Hesperetin.

What condition does NCT05705596 study?

NCT05705596 studies Blood Glucose Fluctuations, Hunger.

Is NCT05705596 still recruiting?

NCT05705596 is currently completed. Last updated 28 November 2023.

Last reviewed 2023-11-28 · How we verify

NCT05705596

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of Hesperetin in Combination With Sucrose on Energy Metabolism

Completed EARLY_PHASE1 Last updated 28 November 2023

What this trial tests

EARLY_PHASE1 trial testing Sucrose in Blood Glucose Fluctuations in 33 participants. Completed in 15 November 2023.

Timeline

31 January 2023

Primary endpoint
30 June 2023

15 November 2023

Quick facts

Lead sponsor	University of Vienna
Phase	EARLY_PHASE1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	basic science
Enrollment	33
Start date	31 January 2023
Primary completion	30 June 2023
Estimated completion	15 November 2023
Sites	1 location across Austria

Drugs / interventions tested

Sucrose — full drug profile →
Hesperetin (Hesperetin) — full drug profile →

Conditions studied

Blood Glucose Fluctuations — all drugs for Blood Glucose Fluctuations →
Hunger — all drugs for Hunger →

Sponsor

University of Vienna

Who can join

Adults 18 to 45, male only, with Blood Glucose Fluctuations or Hunger. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this cross-over intervention study is to investigate the influence of the sweet-modulating substance hesperetin in combination with sucrose in comparison to an equally sweet-tasting sucrose-only solution on markers of energy metabolism.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Sucrose reduction with maintained sweetness level lowers glycemic fluctuations and energy intake in healthy males.
Gaider M, Kimmeswenger I, Schmidt J, Thines C, et al · · 2025 · PMID 41256921 · DOI 10.3389/fnut.2025.1682297

Verify or expand the search:

Other trials of Sucrose

Trials testing the same drug.

NCT06724705 — Testing the Capability of the Smart Underwear Device to Detect Increased Microbiome Activity Following Lactose Consumpti · NA · recruiting
NCT06477770 — Sucrose as a Standard in Cesarean Section Surgical Wound Healing to Reduce Hospital Time · NA · active not recruiting
NCT06107231 — WHNRC (Western Human Nutrition Research Center) Honey Study · NA · active not recruiting
NCT05671965 — Effects of Oral Xylitol on Subsequent Energy Intake · NA · completed
NCT05575687 — Brain and Glycemic Responses to Sweet Soft Drinks · NA · completed

Other University of Vienna trials

Trials by the same sponsor.

NCT06423508 — PRObing The Efficacy of Commercial Stage Storage Buffers and Evaluating Gut Metaproteome Variability Between Individuals · recruiting
NCT06541808 — Balance, Autonomic Response, and Sensory Modulation to Dosage of Mechanical Vagal Stimulation in Healthy Adults · NA · recruiting
NCT06689761 — Influence of Specific Collagen Peptides on Training-Induced Metabolic and Biomechanical Adaptations of Skeletal Muscle · NA · enrolling by invitation
NCT06384365 — Interaction of Inflammation, Taste Perception and Preferences As a Function of Physical Activity and Body Composition · completed
NCT06386237 — Nutritional Modulation of Cognition and Brain Activity · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05705596 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Vienna
Last refreshed: 28 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05705596.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing