NCT05702541 is a NA clinical trial of Lehfilcon A multifocal contact lenses in Presbyopia, sponsored by Alcon Research.

Who is sponsoring NCT05702541?

NCT05702541 is sponsored by Alcon Research.

What drugs are being tested in NCT05702541?

Interventions in NCT05702541: Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system.

What condition does NCT05702541 study?

NCT05702541 studies Presbyopia.

Is NCT05702541 still recruiting?

NCT05702541 is currently completed. Last updated 26 March 2024.

Are results published for NCT05702541?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2024-03-26 · How we verify

NCT05702541

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses

Completed NA Results posted Last updated 26 March 2024

What this trial tests

NA trial testing Lehfilcon A multifocal contact lenses in Presbyopia in 16 participants. Completed in 21 February 2023.

Timeline

24 January 2023

Primary endpoint
21 February 2023

21 February 2023

Quick facts

Lead sponsor	Alcon Research
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	treatment
Enrollment	16
Start date	24 January 2023
Primary completion	21 February 2023
Estimated completion	21 February 2023
Sites	1 location across United States

Drugs / interventions tested

Lehfilcon A multifocal contact lenses
Lotrafilcon B multifocal contact lenses
Hydrogen peroxide-based cleaning and disinfection system

Conditions studied

Presbyopia — all drugs for Presbyopia →

Sponsor

Alcon Research — full company profile →

Who can join

40 and older, any sex, with Presbyopia. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Mean Binocular Visual Acuity (VA) With Study Lenses at 4 Meters (logMAR) Primary · Day 2 of each study lens type worn during the corresponding crossover period

VA was assessed binocularly (both eyes together) using a letter chart and measured in logarithm minimum angle of resolution (logMAR). A logMAR value of 0 equates to 20/20 Snellen visual acuity (normal distance eyesight), with lower logMAR values indicating better visual acuity. No hypothesis testing was pre-specified for this endpoint.

Group	Value	95% CI
LID223194 MF	-0.06	± 0.10
AOHG MF	-0.06	± 0.07

Sponsor's own description

The purpose of this clinical trial is to assess the clinical performance of LID223194 Multifocal (MF) contact lenses and commercially available Air Optix plus HydraGlyde (AOHG) MF contact lenses. Eligible subjects will wear each study lens type in a cross-over fashion as randomized for approximately 2 days.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Lehfilcon A multifocal contact lenses

Trials testing the same drug.

NCT05765227 — Clinical Evaluation of a Manufacturing Process for a Frequent Replacement Silicone Hydrogel Multifocal Contact Lens · NA · completed
NCT05338333 — Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses · NA · completed

Other recruiting trials for Presbyopia

Currently open trials in the same condition.

NCT07444658 — Performance of Two Daily Disposable Multifocal Contact Lenses · NA · recruiting
NCT07284966 — Comfort and Vision With TOTAL30 Multifocal Lenses · recruiting
NCT07077967 — Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections With EDOF IOLs · recruiting
NCT07113210 — Quality of Life in Presbyopic Patients Who Are Treated With Qlosi · Phase 4 · recruiting
NCT06948357 — Efficacy and Safety of BRIMOCHOL PF and CARBACHOL PF in Chinese Presbyopia Patients · Phase 2 · recruiting

Other Alcon Research trials

Trials by the same sponsor.

NCT06884202 — Evaluation of Delefilcon A Contact Lenses · NA · completed
NCT06784063 — Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs) · NA · completed
NCT06571656 — Evaluation of the Safety and Tolerability of Ocular Lubricants · NA · terminated
NCT06660290 — A Study to Evaluate 0.003% AR-15512 Safety and Drop Attributes · Phase 3 · completed
NCT06483113 — DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study · terminated

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05702541 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Alcon Research
Last refreshed: 26 March 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05702541.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing