Last reviewed · How we verify
NCT05700838
Refining Cough Skill Training in Parkinson's Disease and Dysphagia
Phase 1 trial testing Cough Skill Training - with Variable Practice in Parkinson Disease in 23 participants. Completed in 28 June 2023.
28 June 2023
Quick facts
| Lead sponsor | Teachers College, Columbia University |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 23 |
| Start date | 21 September 2022 |
| Primary completion | 28 June 2023 |
| Estimated completion | 28 June 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Cough Skill Training - with Variable Practice
Conditions studied
- Parkinson Disease — all drugs for Parkinson Disease →
- Dysphagia — all drugs for Dysphagia →
Sponsor
Teachers College, Columbia University
Who can join
Adults 40 to 90, any sex, with Parkinson Disease or Dysphagia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Airway protection deficits (cough and swallowing) are prevalent and pervasive in Parkinson's disease (PD), contributing to adverse health outcomes like pneumonia. This study aims to refine cough skill training by examining whether variable versus constant practice conditions improve cough outcomes in people with PD. In addition, this study will provide insight into optimal respiratory adaptations that occur during training to support cough effectiveness, resulting in immediately translatable treatments to improve airway protection-related health outcomes in people with neurodegenerative disease.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Enhancing Cough Motor Learning in Parkinson's Disease Through Variable Practice During Skill Training.
Borders JC, Villarreal-Cavazos K, Huber JE, Quinn L, et al · · 2024 · cited 6× · PMID 39377552 · DOI 10.1002/mdc3.14218
Verify or expand the search:
- PubMed search for NCT05700838
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Parkinson Disease
Currently open trials in the same condition.
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- NCT07432958 — A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (P · Phase 2 · recruiting
Other Teachers College, Columbia University trials
Trials by the same sponsor.
- NCT07488338 — HABIT-ILE + FST in Children With SMA: Preliminary Effectiveness · NA · recruiting
- NCT07478393 — Readiness and Progress in Emotion Regulation Therapy · NA · recruiting
- NCT07223320 — HABIT-ILE + FST in Children With SMA · NA · active not recruiting
- NCT06540989 — Noise-augmented Automatic Speech Recognition for Speech Treatment in Parkinson's Disease · EARLY_PHASE1 · recruiting
- NCT05700825 — Rehabilitation of Airway Protection in Parkinson's Disease · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05700838 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Teachers College, Columbia University
- Last refreshed: 11 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05700838.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing