NCT05700747

Health Through Activity: A Pilot Study of a Rehabilitation Intervention for People Living With Multiple Myeloma

Completed NA Results posted Last updated 16 December 2025

What this trial tests

NA trial testing Health Through Activity in Multiple Myeloma in 5 participants. Completed in 28 March 2025.

Timeline

1 February 2023

Primary endpoint
28 March 2025

28 March 2025

Quick facts

Lead sponsor	MGH Institute of Health Professions
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	health services research
Enrollment	5
Start date	1 February 2023
Primary completion	28 March 2025
Estimated completion	28 March 2025
Sites	1 location across United States

Drugs / interventions tested

• Health Through Activity

Conditions studied

• Multiple Myeloma — all drugs for Multiple Myeloma →

Sponsor

MGH Institute of Health Professions

Who can join

18 and older, any sex, with Multiple Myeloma. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Rate of Participant Enrollment Primary · At screening

Number participants enrolled / Number screened positive \& eligible. A rate of at least 75% will indicate feasibility.

Group	Value	95% CI
Health Through Activity (HTA) Intervention	5

Assessment Completion Rate Primary · Up to 4 months

Defined as the number of participants completing each of the three study assessments to number of participants enrolled. A completion rate of 85% will indicate feasibility.

Group	Value	95% CI
Health Through Activity (HTA) Intervention	5

Screening Rate Primary · Up to 4 months

Number patients screened/ Number patients identified as potentially eligible. Screening rate of at least 75% will indicate feasibility

Group	Value	95% CI
Health Through Activity (HTA) Intervention	11

Eligibility Rate Primary · Up to 4 months

Number patients screening positive \& eligible / Number screened. Eligibility rate is influenced by how many people in the clinical population are experiencing disability. Based on our pilot study, expected rate to be at least 35%.

Group	Value	95% CI
Health Through Activity (HTA) Intervention	5

Intervention Completion Rate Secondary · Up to 3 months

Defined as at least 75% of participants complete all six sessions of Health Through Activity (HTA) and if the mean number of sessions is greater than or equal to 4.

Group	Value	95% CI
Health Through Activity (HTA) Intervention	5

Participant Satisfaction Secondary · Up to 4 months

Assessed by the Satisfaction survey which is a 7-item survey that is rated on a 5-point Likert scale. Any item on the Satisfaction survey that generates a mean score of \< 4 will trigger consideration of modification to the HTA program.

Participants felt well supported by the interventionists

Group	Value	95% CI
Health Through Activity (HTA) Intervention	5

Participants described feeling connected to the interventionists.

Group	Value	95% CI
Health Through Activity (HTA) Intervention	3

Optimism and openness of interventionists kept participants engaged

Group	Value	95% CI
Health Through Activity (HTA) Intervention	3

Participants felt the program structure was both effective and adaptable to their needs

Group	Value	95% CI
Health Through Activity (HTA) Intervention	5

Participants identified areas of growth

Group	Value	95% CI
Health Through Activity (HTA) Intervention	5

The program catalyzed participants to stay engaged, take action, and reflect on progress

Group	Value	95% CI
Health Through Activity (HTA) Intervention	5

Suggestion to tailor messaging/advertising for better clarity of target audience.

Group	Value	95% CI
Health Through Activity (HTA) Intervention	1

Suggestion to highlight that the program can be adapted to various performance levels

Group	Value	95% CI
Health Through Activity (HTA) Intervention	2

Sponsor's own description

The purpose of this study is to explore whether a structured program can help reduce the challenges of decreased physical functioning and quality of life for participants with multiple myeloma by providing a customized exercise program and fostering engagement in meaningful activities.

The name of the study intervention involved in this study is:

Health Through Activity (HTA) (six-session, rehabilitation exercise regimen)

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.