Last reviewed · How we verify
NCT05698719
Validation of vFFR as Compared to FFR to Guide Revascularization of Non-culprit Lesions in STEMI Patients
trial in ST Elevation Myocardial Infarction in 111 participants. Status unknown.
22 June 2023
Quick facts
| Lead sponsor | Erasmus Medical Center |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 111 |
| Start date | 22 June 2022 |
| Primary completion | 22 June 2023 |
| Estimated completion | 22 June 2023 |
| Sites | 2 locations across Netherlands, Poland |
Conditions studied
- ST Elevation Myocardial Infarction — all drugs for ST Elevation Myocardial Infarction →
- Multivessel Coronary Artery Disease — all drugs for Multivessel Coronary Artery Disease →
- Percutaneous Coronary Intervention — all drugs for Percutaneous Coronary Intervention →
Sponsor
Erasmus Medical Center
Who can join
18 and older, any sex, with ST Elevation Myocardial Infarction or Multivessel Coronary Artery Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This prospective multicenter observational cohort study is designed to study the diagnostic performance of acute-setting angiography-based FFR (e.g. vFFR) for the physiological assessment of intermediate non-culprit lesions in STEMI patients, with acute-setting FFR and acute-setting NHPR (e.g. RFR) as the reference standards.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Acute-setting vs. staged-setting vessel fractional flow reserve of intermediate non-culprit lesions in patients with ST-segment elevation myocardial infarction (FAST STAGED study).
Huang J, Groenland FTW, Scoccia A, Ziedses des Plantes AC, et al · · 2023 · cited 4× · PMID 36936376 · DOI 10.1016/j.ijcha.2023.101192 -
Validation of angiography-based FFR in non-culprit vessels of patients presenting with STEMI.
van der Eijk JA, Groenland FTW, Scoccia A, Ziedses des Plantes AC, et al · · 2025 · PMID 40924133 · DOI 10.1007/s00392-025-02729-x
Verify or expand the search:
- PubMed search for NCT05698719
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for ST Elevation Myocardial Infarction
Currently open trials in the same condition.
- NCT05785897 — STEMI Treated With a Polymer-free Sirolimus-coated Stent and P2Y12 Inhibitor-based SAPT Versus Conventional DAPT · NA · recruiting
- NCT06795035 — Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution · recruiting
- NCT07058857 — The Effect of Low-Level Tragus Stimulation on Echocardiographic Parameters in Patients With ST-Segment Elevation Myocard · NA · recruiting
- NCT06465303 — A Study of RTP-026 to Assess Safety, Tolerability and Efficacy in Patients With ST-Elevation Myocardial Infarction (STEM · Phase 2 · recruiting
- NCT06535503 — Clinical Characteristics and Outcomes Among STEMI Patients With Cardiogenic Shock at Abu Dhabi City · recruiting
Other Erasmus Medical Center trials
Trials by the same sponsor.
- NCT07406269 — Clinical Evaluation of AI Decision Support for Early Rehabilitation After Surgery · NA · not yet recruiting
- NCT07402109 — CBCT Guided Markerless SBRT for Renal Cell Cancer · NA · recruiting
- NCT07383194 — Prediction Models for LDLT Outcomes · not yet recruiting
- NCT07426575 — Evaluating the Usability of New Dialysis Bags · not yet recruiting
- NCT07329296 — The Regenerative Capacity of the Donor Liver After Living Donor Liver Transplantation: an Ambidirectional Cohort Study · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05698719 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Erasmus Medical Center
- Last refreshed: 26 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05698719.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing