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NCT05697224

Aschistosoma Haematobiumspecific microRNAas a Tumor Marker for Early Diagnosis and Prognosis of Bilharzial Bladder Cancer in Eygpt

Status unknown NA Last updated 25 January 2023
What this trial tests

NA trial testing urinary micro RNA detection in Bladder Cancer in 50 participants. Status unknown.

Timeline
1 February 2023
Primary endpoint
1 February 2024
1 May 2024

Quick facts

Lead sponsorSohag University
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposediagnostic
Enrollment50
Start date1 February 2023
Primary completion1 February 2024
Estimated completion1 May 2024

Drugs / interventions tested

Conditions studied

Sponsor

Sohag University

Who can join

Eligibility, any sex, with Bladder Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

miRNAs have been detected in different bodily fluids, which suggests significant potential, such as their use as biomarkers in diagnostics and prognostics. Sha-mir-71a was abundantly found in the urine of patients with bladder cancer as compared to benign bladder cystitis associated with schistosomiasis . Additionally, this miRNA was more highly detected in urine samples from patients with bilharzial bladder cancer than bladder cancer not associated with bilharziasis (schistosomiasis), suggesting its specificity in the identification of bladder cancer associated with infection.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. RNA modifications in cancer.
    Wu H, Chen S, Li X, Li Y, et al · · 2025 · cited 5× · PMID 39802639 · DOI 10.1002/mco2.70042
  2. Targeting Regulatory Noncoding RNAs in Human Cancer: The State of the Art in Clinical Trials.
    Piergentili R, Sechi S. · · 2025 · cited 2× · PMID 40284466 · DOI 10.3390/pharmaceutics17040471
  3. Role of non-coding RNA through nanomedicine: the novel therapeutic and diagnostic approaches.
    Khoshnevisan K, Eslamizade MJ, Shams F. · · 2025 · cited 1× · PMID 41185871 · DOI 10.34172/bi.31239

Verify or expand the search:

Other recruiting trials for Bladder Cancer

Currently open trials in the same condition.

Other Sohag University trials

Trials by the same sponsor.

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Data sources for this page

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