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NCT05697224
Aschistosoma Haematobiumspecific microRNAas a Tumor Marker for Early Diagnosis and Prognosis of Bilharzial Bladder Cancer in Eygpt
NA trial testing urinary micro RNA detection in Bladder Cancer in 50 participants. Status unknown.
1 February 2024
Quick facts
| Lead sponsor | Sohag University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 50 |
| Start date | 1 February 2023 |
| Primary completion | 1 February 2024 |
| Estimated completion | 1 May 2024 |
Drugs / interventions tested
- urinary micro RNA detection
Conditions studied
- Bladder Cancer — all drugs for Bladder Cancer →
Sponsor
Sohag University
Who can join
Eligibility, any sex, with Bladder Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
miRNAs have been detected in different bodily fluids, which suggests significant potential, such as their use as biomarkers in diagnostics and prognostics. Sha-mir-71a was abundantly found in the urine of patients with bladder cancer as compared to benign bladder cystitis associated with schistosomiasis . Additionally, this miRNA was more highly detected in urine samples from patients with bilharzial bladder cancer than bladder cancer not associated with bilharziasis (schistosomiasis), suggesting its specificity in the identification of bladder cancer associated with infection.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
RNA modifications in cancer.
Wu H, Chen S, Li X, Li Y, et al · · 2025 · cited 5× · PMID 39802639 · DOI 10.1002/mco2.70042 -
Targeting Regulatory Noncoding RNAs in Human Cancer: The State of the Art in Clinical Trials.
Piergentili R, Sechi S. · · 2025 · cited 2× · PMID 40284466 · DOI 10.3390/pharmaceutics17040471 -
Role of non-coding RNA through nanomedicine: the novel therapeutic and diagnostic approaches.
Khoshnevisan K, Eslamizade MJ, Shams F. · · 2025 · cited 1× · PMID 41185871 · DOI 10.34172/bi.31239
Verify or expand the search:
- PubMed search for NCT05697224
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05697224 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sohag University
- Last refreshed: 25 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05697224.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing