Last reviewed · How we verify
NCT05695664
Postoperative Analgesic Effects of Ibuprofen Versus Ketorolac in Patients Undergoing in Orthopedic Surgery
EARLY_PHASE1 trial testing Ibuprofen 800 mg in Intravenous Drug Usage in 100 participants. Completed in 31 January 2022.
31 January 2022
Quick facts
| Lead sponsor | Benazir Bhutto Hospital, Rawalpindi |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 1 August 2021 |
| Primary completion | 31 January 2022 |
| Estimated completion | 31 January 2022 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Ibuprofen 800 mg — full drug profile →
- Ketorolac Injection — full drug profile →
Conditions studied
- Intravenous Drug Usage — all drugs for Intravenous Drug Usage →
- Ibuprofen — all drugs for Ibuprofen →
- Ketorolac — all drugs for Ketorolac →
- Knee Arthroscopy — all drugs for Knee Arthroscopy →
Sponsor
Benazir Bhutto Hospital, Rawalpindi
Who can join
Adults 40 to 80, any sex, with Intravenous Drug Usage or Ibuprofen. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Objectives: To compare the postoperative analgesic effects of ibuprofen versus ketorolac in patients undergoing orthopedic surgery at Combined Military Hospital, Rawalpindi. Study design: Randomized controlled trial Setting: Department of Anasthesiology, Combined military Hospital, Rawalpindi Duration of study:6 months (01st August 2021 to 31st January 2022) Material and methods: After ethical approval, 100 patients in randomly divided two equal groups (A and B) were selected. In group A, 800 mg IV ibuprofen while in group B, 30 mg IV ketorolac was given within 30 min of skin closure after orthopedic surgery. The pain was assessed via visual analogue scale postoperatively. The SPSS version 25 was used for analysis of data. P value ≤ 0.05 was considered as significant.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05695664
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Ibuprofen 800 mg
Trials testing the same drug.
- NCT06088732 — Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression · Phase 1, PHASE2 · recruiting
- NCT06060236 — Dexketoprofen and Ibuprofen in Long Bone Fractures · Phase 4 · unknown
- NCT05907993 — Ibuprofen Versus Ketorolac For Postoperative Pain Relief After Cesarean Section · Phase 4 · completed
- NCT05610384 — Ibuprofen Versus Ketorolac for Perioperative Pain Control After Open Hysterectomy · NA · completed
- NCT05630222 — Evaluation of Effect of Intravenous Morphine vs Intravenous Ibuprofen and Acetaminophen vs Intravenous Ibuprofen · Phase 3 · completed
Other recruiting trials for Intravenous Drug Usage
Currently open trials in the same condition.
- NCT05657106 — Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk · NA · active not recruiting
- NCT03981445 — Integrated HIV Prevention and HCV Care for PWID · NA · active not recruiting
- NCT03993925 — Enhancing Access to Care for Chronic Hepatitis C Infected Populations in Hong Kong · active not recruiting
Other Benazir Bhutto Hospital, Rawalpindi trials
Trials by the same sponsor.
- NCT06790615 — Comparison of Thread Technique Versus Aspiration Plus Steroid Injection for Wrist Ganglion Recurrence · Phase 1, PHASE2 · completed
- NCT04850131 — Desarda Repair Compared to Lichtenstein Repair for the Treatment of Inguinal Hernias · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05695664 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Benazir Bhutto Hospital, Rawalpindi
- Last refreshed: 25 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05695664.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing