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NCT05691621

Galectin-3 in Septic and Non-septic Acute Kidney Injury

Status unknown Last updated 20 January 2023
What this trial tests

trial testing Standard Reagents, Whole Blood in Acute Kidney Injury in 150 participants. Status unknown.

Timeline
1 January 2023
Primary endpoint
31 August 2023
31 August 2023

Quick facts

Lead sponsorFengyun Wang
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment150
Start date1 January 2023
Primary completion31 August 2023
Estimated completion31 August 2023
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Fengyun Wang — full company profile →

Who can join

Adults 18 to 85, any sex, with Acute Kidney Injury or Sepsis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute kidney injury (AKI) is a common critical condition with high morbidity and mortality. The level of circulating Galectin-3 (Gal3) largely depends on renal function, so it is elevated in patients with AKI or CKD; elevated Gal3 also aggravates the progression of CKD after the onset of AKI. The proinflammatory and profibrotic properties of Gal3 may render it to be one of the key molecules mediating AKI, CKD, and cardiorenal syndrome. In this prospective observational study, the investigators will explore the differences of Gal3 levels among septic AKI, non-septic AKI, and non-AKI patients and its correlation with prognosis, inflammation, and disease severity in the ICU.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Currently open trials in the same condition.

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