NCT05691348 (SAMBA) is a NA clinical trial of Ambulatory appendectomy in Appendicitis, sponsored by Centre Hospitalier Universitaire de Nice.

Who is sponsoring NCT05691348?

NCT05691348 is sponsored by Centre Hospitalier Universitaire de Nice.

What drugs are being tested in NCT05691348?

Interventions in NCT05691348: Ambulatory appendectomy, Conventional appendectomy.

What condition does NCT05691348 study?

NCT05691348 studies Appendicitis.

Is NCT05691348 still recruiting?

NCT05691348 is currently recruiting now. Last updated 31 March 2026.

Last reviewed 2026-03-31 · How we verify

NCT05691348: SAMBA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Same Day Ambulatory Appendectomy (SAMBA)

Recruiting now NA Last updated 31 March 2026

What this trial tests

NA trial testing Ambulatory appendectomy in Appendicitis in 1,400 participants. Currently enrolling.

Timeline

17 July 2023

Primary endpoint
17 January 2028

17 January 2028

Quick facts

Lead sponsor	Centre Hospitalier Universitaire de Nice
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	1,400
Start date	17 July 2023
Primary completion	17 January 2028
Estimated completion	17 January 2028
Sites	33 locations across France, Reunion

Drugs / interventions tested

Ambulatory appendectomy
Conventional appendectomy

Conditions studied

Appendicitis — all drugs for Appendicitis →

Sponsor

Centre Hospitalier Universitaire de Nice

Who can join

Adults 15 to 74, any sex, with Appendicitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The potential benefit of outpatient care for this common digestive emergency is considerable, both for the patients themselves and for the public health system: 1. Optimization of the care pathway, reducing the length of stay in hospital (a major issue in the context of the COVID-19 (coronavirus disease) pandemic) liberating patient beds and staff, and reducing the risk of nosocomial exposure. 2. Improved patient satisfaction compared to waiting for hours in the emergency department due to lack of hospital beds. 3. Non-inferiority of care in an outpatient unit in terms of quality and safety in day hospitalization. 4. Significant decrease in the overall cost of this pathology as a result of a reduction in the hospital stay.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

SAME day amBulatory c (SAMBA): a multicenter, prospective, randomized clinical trial protocol.
Arvieux C, Tidadini F, Barbois S, Fontas E, et al · · 2024 · cited 2× · PMID 39252106 · DOI 10.1186/s13063-024-08336-x

Verify or expand the search:

Other recruiting trials for Appendicitis

Currently open trials in the same condition.

NCT07115303 — Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump Closure · NA · recruiting
NCT06395636 — Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients · NA · recruiting
NCT07049965 — Comparative Study of Harmonic Scalpel vs. Suture Ligation for Appendix Base During Laparoscopic Appendectomy · NA · active not recruiting
NCT07478029 — Clinical Study of PEG Bowel Preparation in Appendectomy Patients · recruiting
NCT06177418 — Transumbilical Laparoscopic Appendectomy · NA · recruiting

Other Centre Hospitalier Universitaire de Nice trials

Trials by the same sponsor.

NCT05897996 — Percutaneous Anastomosis Creation for Hemodialysis Access · NA · withdrawn
NCT07499869 — INNOVATIVE BENEFITS OF A 4D VIRTUAL SIMULATOR · NA · not yet recruiting
NCT07492251 — Upadacitinib in Adult Patients With Erosive Mucosal Lichen Planus and Lichen Planopilaris: a Prospective Multicenter Ran · Phase 2 · not yet recruiting
NCT07511608 — Development of a New Technique for Quantifying Mitochondrial DNA in Single Muscle Fibers · NA · not yet recruiting
NCT07582406 — Codesign, Physical Activity, and Seniors · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05691348 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Nice
Last refreshed: 31 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05691348.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing