NCT05687812

Effects of Cephalaria Syriaca Flour-added Bread on Glucose Metabolism and Appetite Parameters in Individuals With Obesity, Diabetes, and Healthy Controls.

Completed NA Last updated 19 January 2023

What this trial tests

NA trial testing Cephalaria Syriaca flour-added bread in Nutrition, Healthy in 60 participants. Completed in 31 December 2022.

Timeline

1 January 2022

Primary endpoint
31 December 2022

31 December 2022

Quick facts

Lead sponsor	Istanbul University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	crossover
Masking	none
Primary purpose	supportive care
Enrollment	60
Start date	1 January 2022
Primary completion	31 December 2022
Estimated completion	31 December 2022
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Cephalaria Syriaca flour-added bread

Conditions studied

• Nutrition, Healthy — all drugs for Nutrition, Healthy →

Sponsor

Istanbul University

Who can join

Adults 18 to 65, any sex, with Nutrition, Healthy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cephalaria Syriaca is a common weed in Anatolia and grows wild in wheat fields, with high fat, protein, and dietary fiber content. This study it is aimed to evaluate the effects of lowering the glycemic index of white bread consumed in large quantities in Turkey by adding Cephalaria Syriaca, on healthy, obese, and diabetic individuals.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Acute Effects of Pelemir-Enriched Bread on Postprandial Glucose and Hormonal Responses in Adults with Obesity, Type 2 Diabetes, and Normal Weight: A Two-Phase Exploratory Study.
   Soyluk Selcukbiricik O, Calikoglu F, Idiz C, Dura G, et al · · 2025 · PMID 40944207 · DOI 10.3390/nu17172819