Last reviewed · How we verify
NCT05687617
Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma.
Phase 2 trial testing Indocyanine green in Gastric Cancer in 11 participants. Terminated before completion.
27 March 2024
Quick facts
| Lead sponsor | Laval University |
|---|---|
| Phase | Phase 2 |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 11 |
| Start date | 15 December 2022 |
| Primary completion | 27 March 2024 |
| Estimated completion | 27 March 2024 |
| Sites | 2 locations across Canada |
Drugs / interventions tested
- Indocyanine green (INDOCYANINE GREEN) — full drug profile →
Conditions studied
- Gastric Cancer — all drugs for Gastric Cancer →
- Gastric Adenocarcinoma — all drugs for Gastric Adenocarcinoma →
- Peritoneal Carcinomatosis — all drugs for Peritoneal Carcinomatosis →
- Peritoneal Metastases — all drugs for Peritoneal Metastases →
Sponsor
Laval University
Who can join
18 and older, any sex, with Gastric Cancer or Gastric Adenocarcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Peritoneal disease at initial presentation for patients with gastric adenocarcinoma (GA) is frequent, with 15-31% of patients presenting with peritoneal metastases (PM) at surgical exploration. The prognosis of patients with PM is poor, overall survival (OS) ranging from 8 to 13 months, reinforcing the importance of optimal patient selection before surgical management of GA. Indocyanine Green (ICG) fluorescence imaging for intraoperative detection of PM has been described in recent literature as a useful tool in patients undergoing cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal malignancies to increase the detection of PM during surgery. However, the role of ICG for patients with GA, and its role during diagnosic laparoscopy (DL), remain unknown.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Potential Probes for Targeted Intraoperative Fluorescence Imaging in Gastric Cancer.
Martinelli S, Fortuna L, Coratti F, Passagnoli F, et al · · 2024 · cited 4× · PMID 39766041 · DOI 10.3390/cancers16244141
Verify or expand the search:
- PubMed search for NCT05687617
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Indocyanine green
Trials testing the same drug.
- NCT06164392 — Evaluation of Neuroma Perfusion with Indocyanine Green Fluorescence Angiography · Phase 4 · withdrawn
- NCT06169735 — Does Fluorescence With or Without Indocyanine Green Improve Parathyroid Identification and Preservation · Phase 4 · recruiting
- NCT06322862 — FLuorescence Guided Assessment of Mesenteric Ischemia in Emergency Surgery · NA · recruiting
- NCT06227338 — ICG-fluorescence Imaging for Intraoperative Breast Cancer Margins Evaluation: a Dose-timing Study · NA · recruiting
- NCT06939946 — Intraoperative Parathyroid Gland (PTG) Identification Using a Hand-Held Imager (HHI) · Phase 1 · terminated
Other recruiting trials for Gastric Cancer
Currently open trials in the same condition.
- NCT07525765 — AI-assisted Decision-making of Reoperation for Postoperative Bleeding of Gastric Cancer · recruiting
- NCT07464470 — Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Gastroesophageal Cancers · recruiting
- NCT07432633 — [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications · Phase 1, PHASE2 · recruiting
- NCT07431281 — Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Meta · Phase 3 · recruiting
- NCT07448493 — Local Treatment Strategies for Brain Metastases of Gastric and Esophageal Cancer · active not recruiting
Other Laval University trials
Trials by the same sponsor.
- NCT07491887 — Identification of Objective Metabolomics-based Biomarkers of Yogurt Consumption · NA · not yet recruiting
- NCT07366827 — Effectiveness of Motorised Lumbar Support for Non-specific Low Back Pain · NA · not yet recruiting
- NCT07317973 — A Study About Patient Decision Aids Designed to Help Parents and Guardians in Canada Make Evidence-informed, Values-cong · NA · not yet recruiting
- NCT07293312 — Optimizing the Use of Virtual Reality in Rehabilitation for Individuals With Persistent Shoulder Pain · NA · not yet recruiting
- NCT07201870 — Digital Preparation for Bariatric Surgery: Feasability Pilot Trial · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05687617 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Laval University
- Last refreshed: 2 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05687617.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing