NCT05687487 is a clinical trial in Hypertrophic Obstructive Cardiomyopathy, sponsored by Chinese Academy of Medical Sciences, Fuwai Hospital.

Who is sponsoring NCT05687487?

NCT05687487 is sponsored by Chinese Academy of Medical Sciences, Fuwai Hospital.

What condition does NCT05687487 study?

NCT05687487 studies Hypertrophic Obstructive Cardiomyopathy.

Is NCT05687487 still recruiting?

NCT05687487 is currently completed. Last updated 18 January 2023.

Last reviewed 2023-01-18 · How we verify

NCT05687487

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Residual or Recurrent Obstruction After Septal Myectomy

Completed Last updated 18 January 2023

What this trial tests

trial in Hypertrophic Obstructive Cardiomyopathy in 56 participants. Completed in 1 February 2021.

Timeline

1 January 2013

Primary endpoint
31 December 2020

1 February 2021

Quick facts

Lead sponsor	Chinese Academy of Medical Sciences, Fuwai Hospital
Status	Completed
Study type	OBSERVATIONAL
Enrollment	56
Start date	1 January 2013
Primary completion	31 December 2020
Estimated completion	1 February 2021

Conditions studied

Hypertrophic Obstructive Cardiomyopathy — all drugs for Hypertrophic Obstructive Cardiomyopathy →

Sponsor

Chinese Academy of Medical Sciences, Fuwai Hospital

Who can join

Under 14, any sex, with Hypertrophic Obstructive Cardiomyopathy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this observational study is to report the outcomes after septal myectomy in young children and infants and identify the mechanisms of residual or recurrent obstruction after surgery. in The main question\[s\] it aims to answer are: * What is the early and mid-term results of septal myectomy in young children and infants with severe and extensive obstructive hypertrophic cardiomyopathy (HCM)? * What are the mechanisms of residual or recurrent obstruction? Echocardiography and clinical course of children and infants under the age of 14 who underwent septal myectomy for hypertrophic obstructive cardiomyopathy from January 2013 to December 2020 will be followed up.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Residual or recurrent obstruction after septal myectomy in young children and infants with hypertrophic cardiomyopathy: cohort study.
Dong S, Du C, Song J, Dong J, et al · · 2023 · cited 4× · PMID 37165977 · DOI 10.1097/js9.0000000000000426
Left ventricular posterior wall hypertrophy leads to poor prognosis of hypertrophic obstructive cardiomyopathy in children: a cohort study.
Liu S, Hua X, Zhao Y, Mo H, et al · · 2025 · PMID 38905490 · DOI 10.1097/js9.0000000000001862

Verify or expand the search:

Other recruiting trials for Hypertrophic Obstructive Cardiomyopathy

Currently open trials in the same condition.

NCT05332691 — Transapical Beating-heart Septal Myectomy in Patient With Hypertrophic Obstructive Cardiomyopathy · NA · recruiting
NCT05257772 — Electromechanically Optimised Right Ventricular Pacing In Hypertrophic Cardiomyopathy (EMORI-HCM) · NA · active not recruiting

Other Chinese Academy of Medical Sciences, Fuwai Hospital trials

Trials by the same sponsor.

NCT07450196 — A Prospective, Multicenter, Observational Study Evaluating Safety and Effectiveness of SAPIEN 3 Transcatheter Aortic Val · not yet recruiting
NCT07511309 — FFR-Guided Revascularization in Atherosclerotic Renal Artery Stenosis: A Randomized Controlled Trial · NA · not yet recruiting
NCT07054541 — A Novel Echocardiography-Guided Strategy for Percutateous Closure of Atrial Septal Defect Assisted by PannaWire · Phase 4 · not yet recruiting
NCT07458672 — TAVR for Aortic Regurgitation Under TTE Guidance · NA · not yet recruiting
NCT07462325 — Proteomic and Inflammatory Omics Changes With Colchicine Therapy in Coronary Heart Disease · Phase 4 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05687487 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Chinese Academy of Medical Sciences, Fuwai Hospital
Last refreshed: 18 January 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05687487.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing