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NCT05687045
High Flow Nasal Cannula in Patients Undergoing Colonoscopy
NA trial testing High Flow Nasal Cannula in Colonoscopy in 36 participants. Status unknown.
30 June 2023
Quick facts
| Lead sponsor | University Magna Graecia |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 36 |
| Start date | 1 February 2023 |
| Primary completion | 30 June 2023 |
| Estimated completion | 30 June 2023 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- High Flow Nasal Cannula
- Conventional Oxygen Therapy
Conditions studied
- Colonoscopy — all drugs for Colonoscopy →
Sponsor
University Magna Graecia
Who can join
18 and older, any sex, with Colonoscopy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
During colonoscopy, the insertion of the fiberscope and colon distension required to perform the examination may induce modifications to respiratory mechanics, respiratory effort and breathing pattern. High-flow nasal cannula (HFNC) therapy is a mixed air-oxygen supply system able to deliver heated humidified gas up to 60 L/min of flow rate, with an inspiratory oxygen fraction (FiO2) ranging from 21% to 100%. Increasing evidence supports the use of HFNC in several clinical conditions and settings. When compared to standard therapy (ST), HFNC results in enhanced gas exchange and improved comfort. No studies have yet assessed the benefits of HFNC versus ST during and after colonoscopy. The investigators designed this unblinded randomized controlled trial to assess whether HFNC, compared to ST, improves oxygenation at the end of the procedure (primary endpoint). Additional endpoints were: 1) the lowest peripheral saturation of oxygen (SpO2) and the number of oxygen desaturations; 2) the changes of end-expiratory lung impedance and tidal impedance assessed by Electrical Impedance Tomography (EIT); 3) the effects on diaphragm function assessed by ultrasound (DUS).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05687045
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of High Flow Nasal Cannula
Trials testing the same drug.
- NCT06310629 — Oxygenation Efficacy of "Intrinseque Health" Non-Rebreathing Mask ("IHNRM") · NA · unknown
- NCT05693298 — High Flow Nasal Cannula in Patients Undergoing Gastroscopy · NA · unknown
- NCT05396274 — High Flow Nasal Oxygen Therapy Undergoing Colonoscopy · NA · unknown
- NCT04657796 — Role of High Flow Nasal Oxygen as a Strategy for Weaning From Invasive Mechan · unknown
- NCT04269681 — RENOVATE Palliative: HFNC vs. Standard Respiratory Support in Patients With Do-Not-Intubate Order and ARF · NA · terminated
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Currently open trials in the same condition.
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- NCT07171853 — The Carbon Footprint Study of Colonoscopy · recruiting
- NCT07355777 — Video Tutorial and Oral Explanation Vs Oral Explanation Alone in Colonoscopy Preparation · NA · recruiting
Other University Magna Graecia trials
Trials by the same sponsor.
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- NCT06274931 — Analysis of the Pulmonary Microbiome · unknown
- NCT05398289 — FOUR-SIX TRIAL for the Treatment of Enterococcal Endocarditis · Phase 4 · not yet recruiting
- NCT05681962 — Practice of Oxygenation and Respiratory Support During Fiberoptic Bronchoscopy · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05687045 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Magna Graecia
- Last refreshed: 17 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05687045.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing