NCT05686252 is a NA clinical trial of Held Position in Extreme Prematurity, sponsored by University College Cork.

Who is sponsoring NCT05686252?

NCT05686252 is sponsored by University College Cork.

What drugs are being tested in NCT05686252?

Interventions in NCT05686252: Held Position.

What condition does NCT05686252 study?

NCT05686252 studies Extreme Prematurity, Extremely Low Birth Weight, Very Low Birth Weight Infant, Premature Birth.

Is NCT05686252 still recruiting?

NCT05686252 is currently completed. Last updated 19 January 2023.

Last reviewed 2023-01-19 · How we verify

NCT05686252

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

RCT: The Effect of Held Position During Kangaroo Care on Physiological Parameters of Premature Infants

Completed NA Last updated 19 January 2023

What this trial tests

NA trial testing Held Position in Extreme Prematurity in 20 participants. Completed in 30 September 2022.

Timeline

16 May 2022

Primary endpoint
30 September 2022

30 September 2022

Quick facts

Lead sponsor	University College Cork
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	supportive care
Enrollment	20
Start date	16 May 2022
Primary completion	30 September 2022
Estimated completion	30 September 2022
Sites	1 location across Ireland

Drugs / interventions tested

Held Position

Conditions studied

Extreme Prematurity — all drugs for Extreme Prematurity →
Extremely Low Birth Weight — all drugs for Extremely Low Birth Weight →
Very Low Birth Weight Infant — all drugs for Very Low Birth Weight Infant →
Premature Birth — all drugs for Premature Birth →

Sponsor

University College Cork

Who can join

28 Weeks and older, any sex, with Extreme Prematurity or Extremely Low Birth Weight. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this superiority crossover randomised controlled trial is to investigate whether there is an optimal position at which to perform kangaroo mother care (KMC) in extremely preterm infants in the NICU. The main question it aims to answer is: 1) is there an optimal position for an infant to be held during KMC and 2) to optimise benefits for infants receiving KMC. Participants will be: 1) randomised into two groups which determine which angle they will start at first, 2) assessed over two hour-long sessions on different days with a change in the angle at the 30 minute point, 3) monitored using a Massimo NIRS machine which will record oxygen saturations, cerebral NIRS values and heart rates, and 4) monitored for any episodes of desaturations and bradycardias during this time. Participants will then be assessed beginning with the the other angle first on a different day. The researchers will then compare the two groups to see if being held at a 30 degrees during KMC is superior to being held at 60 degrees in terms of physiological stability.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

The effect of maternal position on cerebral oxygenation in premature infants during Kangaroo care: a randomised controlled trial.
Stapleton I, Murphy S, Vaughan S, Walsh BH, et al · · 2025 · PMID 40186001 · DOI 10.1038/s41372-025-02287-0
The Effect of Maternal Position on Cerebral Oxygenation in Premature Infants During Kangaroo Care: a Randomised Controlled Trial
Stapleton I, Murphy S, Vaughan S, Walsh B, et al · · 2024 · DOI 10.21203/rs.3.rs-5363349/v1

Verify or expand the search:

Other recruiting trials for Extreme Prematurity

Currently open trials in the same condition.

NCT06512935 — Ventilator Pressure and Optimization of Compliance and Hemodynamics · NA · recruiting
NCT05347238 — Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis · recruiting
NCT04413097 — Delayed Cord Clamping With Oxygen In Extremely Low Gestation Infants · NA · active not recruiting
NCT06027645 — Early Intervention Based on Neonatal Crawling in Very Premature Infants at Risk For Neurodevelopmental Disorder · NA · recruiting
NCT03997266 — NICU Antibiotics and Outcomes Trial · Phase 4 · active not recruiting

Other University College Cork trials

Trials by the same sponsor.

NCT07481240 — A Household-Based Dietary Intervention Study of Vitamin D Fortified Bread in Irish Families · NA · recruiting
NCT06857539 — Assessing Intellectual and Motor Outcomes in High-risk Infants · not yet recruiting
NCT07363928 — A Digital Cognitive Behavioural Therapy for Insomnia Intervention in Mild Cognitive Impairment and Mild Dementia · NA · completed
NCT06705582 — OASIS Study: Vitamin D Deficiency Prevention Among Older Adults in Ireland · NA · completed
NCT06709209 — AI-driven Narrow-band Imaging Score for Disease Assessment and Outcome Prediction in Ulcerative Colitis · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05686252 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University College Cork
Last refreshed: 19 January 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05686252.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing