NCT05684120 (ML-UP) is a NA clinical trial of Mood Lifters for Undergraduates in Depression, sponsored by University of Michigan.

Who is sponsoring NCT05684120?

NCT05684120 is sponsored by University of Michigan.

What drugs are being tested in NCT05684120?

Interventions in NCT05684120: Mood Lifters for Undergraduates.

What condition does NCT05684120 study?

NCT05684120 studies Depression, Anxiety, Mood Disorders, Mental Health Wellness 1, Stress.

Is NCT05684120 still recruiting?

NCT05684120 is currently completed. Last updated 10 December 2025.

Last reviewed 2025-12-10 · How we verify

NCT05684120: ML-UP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Mood Lifters for Undergraduates

Completed NA Last updated 10 December 2025

What this trial tests

NA trial testing Mood Lifters for Undergraduates in Depression in 125 participants. Completed in 18 October 2025.

Timeline

1 August 2023

Primary endpoint
18 October 2025

18 October 2025

Quick facts

Lead sponsor	University of Michigan
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	125
Start date	1 August 2023
Primary completion	18 October 2025
Estimated completion	18 October 2025
Sites	1 location across United States

Drugs / interventions tested

Mood Lifters for Undergraduates

Conditions studied

Depression — all drugs for Depression →
Anxiety — all drugs for Anxiety →
Mood Disorders — all drugs for Mood Disorders →
Mental Health Wellness 1 — all drugs for Mental Health Wellness 1 →

Sponsor

University of Michigan

Who can join

18 and older, any sex, with Depression or Anxiety. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Large-scale, effective, low-cost, and evidence-based programs that can nimbly translate new research discoveries into prevention and care for psychosocial-based problems are urgently needed since the vast majority of people who need evidence-based care do not receive it. The purpose of this randomized control trial is to investigate the feasibility and efficacy of a Mood Lifters group template specifically for undergraduate students. Mood Lifters is an effective peer-led program that improves or maintains mental health. It seeks to help people enhance pleasure, engagement, and meaning in their lives while minimizing depression, fear, loneliness, and other negative feelings via a proprietary peer-based program that offers weekly meetings and other flexible support options. One obstacle to providing mental health care in the US is that it is costly to provide one-on-one therapy by a licensed professional. This is particularly true in large group settings with limited resources (counseling centers) and a large need for mental health care, like universities.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

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Other University of Michigan trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05684120 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Michigan
Last refreshed: 10 December 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05684120.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing