Last reviewed · How we verify
NCT05683145: CU-REST
University of Colorado - Restoring Efficient Sleep After TBI
NA trial testing Computerized Cognitive Behavioral Therapy for Insomnia in Insomnia in 80 participants. Currently enrolling.
1 May 2026
Quick facts
| Lead sponsor | VA Eastern Colorado Health Care System |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 1 July 2022 |
| Primary completion | 1 May 2026 |
| Estimated completion | 1 May 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Computerized Cognitive Behavioral Therapy for Insomnia
Conditions studied
- Insomnia — all drugs for Insomnia →
- Traumatic Brain Injury — all drugs for Traumatic Brain Injury →
Sponsor
VA Eastern Colorado Health Care System — full company profile →
Who can join
Adults 18 to 60, any sex, with Insomnia or Traumatic Brain Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Sleep disturbance is a common condition following traumatic brain injury (TBI) and impairs recovery and quality of life. While efficacious interventions exist many are not accessible to all patients due to a variety of factors (e.g., rurality, access to providers). Further, many of the available treatments have not been validated for individuals with moderate/severe TBI. The proposed study will evaluate a guided computerized version of cognitive behavioral therapy for insomnia (cCBT-I) against enhanced treatment as usual (ETU) in individuals with moderate/severe TBI.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05683145
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Computerized Cognitive Behavioral Therapy for Insomnia
Trials testing the same drug.
- NCT03365024 — Computerized Cognitive Behavioral Treatment for Insomnia: Improving Rural Veteran Access to Evidence-Based Treatment to · NA · completed
- NCT03366870 — Efficacy of a Computerized Cognitive Behavioral Treatment for Insomnia: Increasing Access to Insomnia Treatment to Decre · NA · completed
Other recruiting trials for Insomnia
Currently open trials in the same condition.
- NCT07384429 — Effects of Lemborexant on Motor-sleep Comorbidity in Parkinson's Disease · Phase 4 · recruiting
- NCT07270406 — Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain · NA · recruiting
- NCT07071324 — CF Wellness Program · NA · recruiting
- NCT07417813 — A Multicenter Observational Study of Lemborexant on Insomnia Patients With Psychiatric Disorders · recruiting
- NCT06348082 — Project Women's Insomnia Sleep Health Equity Study (WISHES) · NA · recruiting
Other VA Eastern Colorado Health Care System trials
Trials by the same sponsor.
- NCT06375083 — Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression · Phase 2 · recruiting
- NCT05867134 — Activity Restrictions After Inguinal Hernia Repair · NA · recruiting
- NCT04150380 — Probiotic (LGG) for Veterans With PTSD · Phase 2 · completed
- NCT04281849 — Balance, Aerobic Capacity, Mobility and Strength in Patients Hospitalized for Heart Failure (BAMS-HF) Program · NA · completed
- NCT04159480 — Facilitating Assessment of At-Risk Sailors Using Technology · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05683145 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by VA Eastern Colorado Health Care System
- Last refreshed: 18 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05683145.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing