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NCT05681507
Efficacy of TTMPB in Adult Cardiac Surgery
NA trial testing Transversus thoracic muscle plane block in Acute Post Operative Pain in 140 participants. Status unknown.
31 December 2023
Quick facts
| Lead sponsor | Eric Albrecht |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 140 |
| Start date | 1 December 2022 |
| Primary completion | 31 December 2023 |
| Estimated completion | 31 May 2024 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Transversus thoracic muscle plane block — full drug profile →
- Standard postoperative analgesia — full drug profile →
Conditions studied
- Acute Post Operative Pain — all drugs for Acute Post Operative Pain →
Sponsor
Eric Albrecht — full company profile →
Who can join
Adults 18 to 100, any sex, with Acute Post Operative Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to compare the efficacy of Transversus Thoracic Muscle Plane Block (TTMPB) integrated in a modern multimodal analgesia protocol, following the ERAS® recommendations, in adult patients undergoing planned open heart surgery. The main study question is: Does the addition of TTMPB to a standard analgesic protocol significantly improve analgesia following elective open heart surgery? The investigators will primarily compare postoperative opioid consumption and pain scores in patients who will be randomly allocated to one of two groups: The control group will receive standard analgesia per institutional Intensive Care Unit protocol. The intervention group will receive the same standard of care plus a TTMP block (40ml of bupivacaine 0.375%, total dose of 150 mg). The investigators will also study the impact of group allocation on secondary outcomes, such as the rate of early mobilization.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05681507
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Transversus thoracic muscle plane block
Trials testing the same drug.
- NCT07417462 — Transversus Thoracic Muscle Plane Block Versus Pectointercostal Fascial Block for Enhanced Recovery After Cardiac Surger · NA · recruiting
- NCT06987136 — Transversus Thoracic Muscle Plane Block, Erector Spinae Plane Block and Paravertebral Block for Analgesia in Video-Assis · NA · completed
Other recruiting trials for Acute Post Operative Pain
Currently open trials in the same condition.
- NCT06778629 — Transversalis Fascia Plane Block for Laparoscopic Inguinal Hernia Repair · NA · recruiting
- NCT06515691 — Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy · NA · recruiting
- NCT05141591 — Gender-specific Preoperative Anxiety Level and Postoperative Opioid Requirement After ENT Surgery. · recruiting
- NCT05920200 — Factors Influencing the Results of Treatment in Patients With Hernias of Various Localizations · recruiting
Other Eric Albrecht trials
Trials by the same sponsor.
- NCT05384795 — Perioperative Atelectasis in Orthopaedic Surgery: a Prospective Study · completed
- NCT04726280 — Respiratory Impact of LA Volume After IS Block · Phase 4 · completed
- NCT04394130 — Analgesic Efficacy of Continuous Infusion of Local Anaesthetic Versus Single-shot Injection Interscalene Block · NA · completed
- NCT03527576 — Block Duration After Spinal Block and iv Dexamethasone. · Phase 4 · completed
- NCT03454191 — Efficacy of Erector Spinae Plane Block for Postoperative Analgesia in Adult Patients Undergoing Thoracoscopy · NA · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05681507 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Eric Albrecht
- Last refreshed: 23 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05681507.
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