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NCT05680363
Prospective Sibling Oocyte Study of a New Method to Improve Embryo Development in IVF/ICSI Patients
NA trial testing HyperSperm in Infertility in 41 participants. Completed in 18 December 2025.
18 December 2025
Quick facts
| Lead sponsor | Fecundis S.A. |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 41 |
| Start date | 1 May 2023 |
| Primary completion | 18 December 2025 |
| Estimated completion | 18 December 2025 |
| Sites | 4 locations across Argentina |
Drugs / interventions tested
- HyperSperm
- Standard Sperm Preparation
Conditions studied
- Infertility — all drugs for Infertility →
Sponsor
Fecundis S.A.
Who can join
Adults 20 to 41, any sex, with Infertility. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Prospective, multi-centric, split-sample, sibling oocyte study evaluating the safety and efficacy of a new method to prepare sperm samples for IVF (in vitro fertilization) / ICSI (intracytoplasmic sperm injection) compared to standard procedures.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
A multicenter, prospective sibling oocyte study revealed that HyperSperm<sup>™</sup> improves the number and quality of embryos in patients undergoing in vitro fertilization.
Oscoz-Susino N, Gómez-Elías MD, Bisioli C, Horton M, et al · · 2026 · PMID 42231286 · DOI 10.1186/s12967-026-08261-4 -
A Multicenter, Prospective Sibling Oocyte Study Revealed That Hypersperm™ Improves the Number and Quality of Embryos in Patients Undergoing in Vitro Fertilization.
Susino NO, Elias MG, Bisioli C, Horton M, et al · · 2026 · DOI 10.21203/rs.3.rs-8710462/v1
Verify or expand the search:
- PubMed search for NCT05680363
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Infertility
Currently open trials in the same condition.
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- NCT07340827 — A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH · Phase 3 · recruiting
- NCT07369362 — To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That · NA · active not recruiting
- NCT07153367 — Using a Fixed Dosage of Follitropin Delta for Ovarian Stimulation for Intrauterine Insemination: Rekovelle for Intrauter · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05680363 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fecundis S.A.
- Last refreshed: 8 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05680363.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing