Who is sponsoring NCT05677568?

NCT05677568 is sponsored by Cardiac Dimensions, Inc..

What drugs are being tested in NCT05677568?

Interventions in NCT05677568: Carillon Mitral Contour System.

What condition does NCT05677568 study?

NCT05677568 studies Functional Mitral Regurgitation, Mitral Regurgitation.

Is NCT05677568 still recruiting?

NCT05677568 is currently enrolling by invitation. Last updated 14 March 2023.

Last reviewed 2023-03-14 · How we verify

NCT05677568: CINCH-FMR

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The CINCH-FMR Post-Market Registry: Percutaneous Repair in Functional Mitral Regurgitation

ENROLLING BY INVITATION Last updated 14 March 2023

What this trial tests

trial testing Carillon Mitral Contour System in Functional Mitral Regurgitation in 250 participants. Enrolling by invitation.

Timeline

24 June 2017

Primary endpoint
30 June 2025

30 June 2030

Quick facts

Lead sponsor	Cardiac Dimensions, Inc.
Status	ENROLLING BY INVITATION
Study type	OBSERVATIONAL
Enrollment	250
Start date	24 June 2017
Primary completion	30 June 2025
Estimated completion	30 June 2030
Sites	19 locations across Germany

Drugs / interventions tested

Carillon Mitral Contour System

Conditions studied

Functional Mitral Regurgitation — all drugs for Functional Mitral Regurgitation →
Mitral Regurgitation — all drugs for Mitral Regurgitation →

Sponsor

Cardiac Dimensions, Inc. — full company profile →

Who can join

18 and older, any sex, with Functional Mitral Regurgitation or Mitral Regurgitation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a retrospective and prospective, multi-center, post-market observational registry study. The primary objective of this post market registry is to continue to evaluate the long term safety and performance of the Carillon® Mitral Contour System® (CMCS) in a commercial (post market) setting.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Long-Term Outcomes of Indirect Annuloplasty for Functional Mitral Regurgitation: Interim Results From the CINCH Registry.
Fichtlscherer S, Hicea S, Barbieri F, Yildiz M, et al · · 2025 · PMID 41334349 · DOI 10.1016/j.shj.2025.100738

Verify or expand the search:

Other trials of Carillon Mitral Contour System

Trials testing the same drug.

NCT04529928 — An Initial Evaluation of the Carillon Mitral Contour System for Treatment of Atrial Function Mitral Regurgitation · NA · terminated
NCT03142152 — The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR · NA · recruiting
NCT02325830 — Carillon Mitral Contour System® for Reducing Functional Mitral Regurgitation · NA · completed

Other recruiting trials for Functional Mitral Regurgitation

Currently open trials in the same condition.

NCT06823700 — Safety and Effectiveness Study of SQ-Kyrin System for Functional Mitral Regurgitation in EU · NA · recruiting
NCT05991284 — Sacubitril-Valsartan in Heart Failure With Preserved Ejection Fraction and Secondary Mitral Valve Regurgitation · Phase 4 · active not recruiting
NCT05965258 — Phenotypic Classification of FMR With CMR · recruiting
NCT03929913 — NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility Study · NA · active not recruiting
NCT03706833 — Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial · NA · active not recruiting

Other Cardiac Dimensions, Inc. trials

Trials by the same sponsor.

NCT03142152 — The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05677568 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cardiac Dimensions, Inc.
Last refreshed: 14 March 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05677568.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing