Who is sponsoring NCT05676177?

NCT05676177 is sponsored by Sheba Medical Center.

What drugs are being tested in NCT05676177?

Interventions in NCT05676177: Ultra Low Dose CT, Fat quantification MRI.

What condition does NCT05676177 study?

NCT05676177 studies Non-Alcoholic Fatty Liver Disease, Steatosis of Liver.

Is NCT05676177 still recruiting?

NCT05676177 is currently status unknown. Last updated 12 April 2023.

Last reviewed 2023-04-12 · How we verify

NCT05676177

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

CT Liver Fat Fraction Quantification

Status unknown NA Last updated 12 April 2023

What this trial tests

NA trial testing Ultra Low Dose CT in Non-Alcoholic Fatty Liver Disease in 150 participants. Status unknown.

Timeline

29 January 2023

Primary endpoint
31 December 2024

31 December 2025

Quick facts

Lead sponsor	Sheba Medical Center
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	150
Start date	29 January 2023
Primary completion	31 December 2024
Estimated completion	31 December 2025
Sites	1 location across Israel

Drugs / interventions tested

Ultra Low Dose CT
Fat quantification MRI

Conditions studied

Non-Alcoholic Fatty Liver Disease — all drugs for Non-Alcoholic Fatty Liver Disease →
Steatosis of Liver — all drugs for Steatosis of Liver →

Sponsor

Sheba Medical Center

Who can join

18 and older, any sex, with Non-Alcoholic Fatty Liver Disease or Steatosis of Liver. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Our aim is to develop an AI based tool to use ultra-low dose CT in two separate energy levels using a single-energy CT machine to quantify liver fat in individuals at risk for having non-alcoholic fatty liver disease (NAFLD), compared to MRI which serves as the standard of reference. Secondary aim of our study is to validate the developed artificial intelligence (AI)-based model on a second group of participants ("external validation").

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

[Diagnosis and treatment of liver diseases in the era of artificial intelligence].
Ren LY, Chen DB, Chen HS. · · 2025 · PMID 41461549 · DOI 10.3760/cma.j.cn501113-20250910-00376

Verify or expand the search:

Other recruiting trials for Non-Alcoholic Fatty Liver Disease

Currently open trials in the same condition.

NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting
NCT07294963 — Impact of Lifestyle Interventions on Cognitive Decline in Non-alcoholic Fatty Liver Disease · NA · recruiting
NCT07130318 — Mediterranean Diet in Familial Mediterranean Fever: Is Fatty Liver Affected by Addition of Aerobic Exercise · NA · recruiting
NCT06355310 — Mechanisms of SGLT2 Inhibition in Pediatric Steatotic Liver Disease · Phase 2 · recruiting
NCT06863376 — Evaluating the Safety and Efficacy of Carbocisteine in the Treatment of Nonalcoholic Fatty Liver Disease Patients · Phase 2 · recruiting

Other Sheba Medical Center trials

Trials by the same sponsor.

NCT07401524 — Carbetocin Uterotonic Treatment in Twin Pregnancies for Prevention of Postpartum Hemorrhage · Phase 4 · not yet recruiting
NCT07523373 — Facial Nerve Monitoring During Parotid and Facial Surgery Using a Non-Invasive Patch · NA · not yet recruiting
NCT07509229 — 9-cis Beta-Carotene-Rich Extract of Dunaliella Alga in Retinitis Pigmentosa Patients · Phase 1, PHASE2 · not yet recruiting
NCT07405723 — Arm Position and Blood Pressure Measurement Accuracy During Pregnancy · NA · recruiting
NCT07474987 — Portable VR-based Chromatic Pupilloperimeter for Diagnosis and Monitoring of Traumatic Brain Injury · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05676177 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Sheba Medical Center
Last refreshed: 12 April 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05676177.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing