NCT05675657

Quadratus Lumborum Block vs Erector Spinae Plane Block in Abdominal Hysterectomy

Completed NA Last updated 10 October 2023

What this trial tests

NA trial testing No Block in Gynecologic Disease in 81 participants. Completed in 15 July 2023.

Timeline

15 January 2023

Primary endpoint
15 July 2023

15 July 2023

Quick facts

Lead sponsor	Namik Kemal University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	81
Start date	15 January 2023
Primary completion	15 July 2023
Estimated completion	15 July 2023
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• No Block
• Quadratus Lumborum Block Type III
• Erector Spinae Plane Block — full drug profile →

Conditions studied

• Gynecologic Disease — all drugs for Gynecologic Disease →

Sponsor

Namik Kemal University

Who can join

Adults 18 to 75, female only, with Gynecologic Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Postoperative pain following abdominal hysterectomy is a challenging concern as some patients suffer acute pain that could let to chronic pain over time following the surgery. Epidural analgesia which is the gold standard for postoperative pain management in abdominal surgeries including abdominal hysterectomy has side effects such as hypotension, hematoma, motor weakness of lower limbs, paresthesia, intrathecal placement of the epidural catheter and urinary retention that could prolong hospital stay. Since high frequency ultrasound machines' usage has increased in postoperative analgesia management, ultrasound guided fascial plane blocks has been performed by clinicians with high success rate. To avoid possible complications of epidural catheter placement and epidural analgesia, various techniques has been applying for an analgesic effect close to the effectiveness of epidural analgesia. These techniques include transversus abdominis plane block, rectus sheath block, wound infiltration of local anesthetics, erector spinae plane block and quadratus lumborum plane block. However, each of the plane blocks has limitations individually which prevent them to be the unique analgesic technique for postoperative analgesia following abdominal surgery. As far as the authors knowledge, there's no reported study which compares ultrasound guided erector spinae plane block versus ultrasound guided quadratus lumborum type III block (anterior quadratus lumborum block) as a preemptive analgesia technique in patients undergoing abdominal hysterectomy.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Comparative efficacy of erector spinae plane and quadratus lumborum blocks in managing postoperative pain for total abdominal hysterectomy: A randomized controlled trial.
   Baran O, Şahin A, Arar C. · · 2024 · cited 3× · PMID 39470511 · DOI 10.1097/md.0000000000040313
2. Comparative efficacy of erector spinae plane and quadratus lumborum blocks in managing postoperative pain for total abdominal hysterectomy: A randomized controlled trial
   BARAN O, ŞAHİN A. · · 2024 · DOI 10.21203/rs.3.rs-3933636/v1