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NCT05671328: ASPIC
Incidence of Invasive Pulmonary Aspergillosis in Ventilator-associated Pneumonia
trial testing Biological examinations performed on blood and BAL in Ventilator Associated Pneumonia in 263 participants. Completed in 18 July 2025.
18 July 2025
Quick facts
| Lead sponsor | University Hospital, Lille |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 263 |
| Start date | 28 August 2023 |
| Primary completion | 18 July 2025 |
| Estimated completion | 18 July 2025 |
| Sites | 1 location across France |
Drugs / interventions tested
- Biological examinations performed on blood and BAL
Conditions studied
- Ventilator Associated Pneumonia — all drugs for Ventilator Associated Pneumonia →
- Pulmonary Aspergillosis Invasive — all drugs for Pulmonary Aspergillosis Invasive →
Sponsor
University Hospital, Lille
Who can join
18 and older, any sex, with Ventilator Associated Pneumonia or Pulmonary Aspergillosis Invasive. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Mechanically ventilated patients are at risk of developing ventilator-associated pneumonia (VAP). Invasive pulmonary aspergillosis (IPA), the diagnosis of which motivates the implementation of specific treatments, is one of the causes of VAP. The hypothesis of the study is that the incidence of IPA is 12.4%. For each patient presenting with a suspicion of VAP and requiring a bronchoalveolar lavage (BAL), the diagnosis of API will be evaluated by biological examinations performed on blood and BAL. Medical and surgical history as well as clinical and biological data will be collected for 28 days or until discharge from the ICU.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05671328
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Ventilator Associated Pneumonia
Currently open trials in the same condition.
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- NCT05591924 — Early Severe Illness TrAnslational BioLogy InformaticS in Humans · recruiting
- NCT06092554 — Probiotics to Actively Counter Ventilator Associated Pneumonia (PROACT) · NA · recruiting
- NCT05979545 — EaRly impAct theraPy With Ceftazidime-avibactam Via rapID Diagnostics · Phase 4 · recruiting
Other University Hospital, Lille trials
Trials by the same sponsor.
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- NCT07434739 — PAravertebral CaTheter Versus Epidural Analgesia in Totally Minimally Invasive Esophagectomies · NA · not yet recruiting
- NCT06958224 — Theranostic Approach by Early Multigene Sequencing in Advanced Poor Prognosis Cancers · NA · not yet recruiting
- NCT07408999 — Totally Versus Hybrid Minimally Invasive Esophagectomy for Esophageal Cancer · NA · not yet recruiting
- NCT07492030 — Validation of the Use of the Arteriovenous Tension Difference in CO2 Under Hyperbaric Conditions · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05671328 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Lille
- Last refreshed: 26 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05671328.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing