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NCT05670678
Improved Respiratory Infection by Consuming Lactoferrin Fortified a2 Growing up Formula in Children of 2 to 3 Year Old
trial testing a2 growing up stage 3 formula puls lactoferrin supplement in Respiratory Infection in 200 participants. Completed in 17 May 2023.
17 May 2023
Quick facts
| Lead sponsor | a2 Milk Company Ltd. |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 200 |
| Start date | 19 December 2022 |
| Primary completion | 17 May 2023 |
| Estimated completion | 17 May 2023 |
| Sites | 2 locations across China |
Drugs / interventions tested
- a2 growing up stage 3 formula puls lactoferrin supplement
- Enfinitas growing up stage 3 formula
Conditions studied
- Respiratory Infection — all drugs for Respiratory Infection →
- Diarrheal Disease — all drugs for Diarrheal Disease →
Sponsor
a2 Milk Company Ltd.
Who can join
Adults 2 to 3, any sex, with Respiratory Infection or Diarrheal Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to compare the incidence of ARI and/or diarrheal disease associated with feeding different formulas with and without lactoferrin supplement in children of 2-3 years old. 200 children eligible for the study will be enrolled from two study sites and randomly assigned to two groups (a2 growing up stage 3 formula puls lactoferrin supplement, and Enfinitas growing up stage 3 formula) to feed for 90 days. About 160 children (80 for each group) are expected to finish the study, and data will be collected during the four visits across the study. Researchers will compare the two groups to see if there is significant decrease of the occurrence of diarrheal disease and/or acute respiratory infection for children fed with a2 growing up stage 3 formula puls lactoferrin supplement
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of A1 protein-free formula versus conventional formula on acute respiratory infections and diarrhea in toddlers: A Randomized Controlled Trial.
Yu W, Wang W, Sheng X. · · 2025 · cited 1× · PMID 39895612 · DOI 10.1002/jpn3.12473
Verify or expand the search:
- PubMed search for NCT05670678
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Other a2 Milk Company Ltd. trials
Trials by the same sponsor.
- NCT06256094 — The Effects of a2 Infant Formula on Growth and Tolerance in Healthy Term Infants · NA · completed
- NCT05829720 — Investigate Effects of A2 Milk on Breastmilk Composition and Subsequent Infant Gut Health, Crying and Sleep Patterns in · NA · completed
- NCT05741047 — Comparative Effects of a2 Skim Milk on Mild Cognitive Impairment in Older Adults · NA · completed
- NCT04733937 — Comparative Effects of A2 Platinum Stage 1 Infant Formula on Infant Digestion and Comfort · NA · completed
- NCT06763185 — A1 Beta-casein-free Milk in Milk-intolerant Participants · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05670678 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by a2 Milk Company Ltd.
- Last refreshed: 29 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05670678.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing