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NCT05669287
Defining a Vascular Phenotype of Pancreatic Ductal Adenocarcinoma With CT Perfusion Using Quantitative Radiomics
NA trial testing CT Perfusion in PDAC - Pancreatic Ductal Adenocarcinoma in 125 participants. Status unknown.
31 December 2022
Quick facts
| Lead sponsor | Radboud University Medical Center |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 125 |
| Start date | 22 December 2017 |
| Primary completion | 31 December 2022 |
| Estimated completion | 1 June 2023 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- CT Perfusion
Conditions studied
- PDAC - Pancreatic Ductal Adenocarcinoma — all drugs for PDAC - Pancreatic Ductal Adenocarcinoma →
Sponsor
Radboud University Medical Center
Who can join
18 and older, any sex, with PDAC - Pancreatic Ductal Adenocarcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
With CT-perfusion(CTP) it is possible to visualize the enhancement pattern of the tumor. The perfusion CT, interleaved with a routine contrast enhanced CT (CECT) will be performed at diagnosis in all patients (goal: n=125 patients) and at the first follow-up at 3 months in patients treated with systemic therapy (goal: n=50 patients). Also, the histopathology will be collected for resected tumors to perform histopathology analysis. CTP parameters will be correlated to immunohistological findings and clinical outcome. The main goal of the study is to create an AI-assisted method to classify patients with a vascular phenotype of pancreatic ductal adenocarcinoma (PDAC). The investigators expect that this phenotype can be used to predict overall survival and chemotherapy response.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Automated Quantitative Analysis of CT Perfusion to Classify Vascular Phenotypes of Pancreatic Ductal Adenocarcinoma.
Perik T, Alves N, Hermans JJ, Huisman H. · · 2024 · cited 1× · PMID 38339328 · DOI 10.3390/cancers16030577
Verify or expand the search:
- PubMed search for NCT05669287
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of CT Perfusion
Trials testing the same drug.
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- NCT04323020 — CT Perfusion (CTP) for Assessment of Poor Neurological Outcome in Comatose Cardiac Arrest Patients · NA · completed
- NCT04318665 — Early Diagnosis of Mortality Using Admission CT Perfusion in Severe Traumatic Brain Injury Patients (ACT-TBI Study) · NA · completed
- NCT01923922 — CT Perfusion in the Prognostication of Cerebral High Grade Glioma · NA · completed
Other recruiting trials for PDAC - Pancreatic Ductal Adenocarcinoma
Currently open trials in the same condition.
- NCT07252232 — Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC) · Phase 3 · recruiting
- NCT07243262 — Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma (VAPOR2) · recruiting
- NCT07262957 — Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Inc · Phase 4 · recruiting
- NCT07117045 — Artificial Intelligence-powered Low-Dose Computed Tomography for Screening of Pancreatic Cancer · recruiting
- NCT06122896 — Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals · EARLY_PHASE1 · recruiting
Other Radboud University Medical Center trials
Trials by the same sponsor.
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- NCT07532577 — Intranasal Insulin to Prevent Intensive Care Unit Delirium · Phase 2, PHASE3 · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05669287 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Radboud University Medical Center
- Last refreshed: 3 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05669287.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing