NCT05668299

Determining the Appropriate Setting of an Automated Secretion Removal Technology (TrachFlush)

Completed NA Last updated 29 December 2022

What this trial tests

NA trial testing TrachFlush in Mechanical Ventilation Complication in 20 participants. Completed in 10 February 2022.

Timeline

1 October 2021

Primary endpoint
8 February 2022

10 February 2022

Quick facts

Lead sponsor	Hospitalsenheden Vest
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	20
Start date	1 October 2021
Primary completion	8 February 2022
Estimated completion	10 February 2022
Sites	2 locations across Denmark

Drugs / interventions tested

• TrachFlush

Conditions studied

• Mechanical Ventilation Complication — all drugs for Mechanical Ventilation Complication →
• Intubation Complication — all drugs for Intubation Complication →

Sponsor

Hospitalsenheden Vest

Who can join

18 and older, any sex, with Mechanical Ventilation Complication or Intubation Complication. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Using a new device, the TrachFlush, the aim of this pilot study is to investigate whether secretions can be removed at the patient's current ventilator settings, or whether pressures and durations considered at the maximal end of clinical practice are required, so as to push secretions around the cuff. The study is a pilot study to investigate the settings required to ensure clinical efficacy of the technology, prior to large scale clinical studies.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Efficacy of an Automated Secretion Removal Technology at Different Inspiratory Pressures.
   Nielsen AH, Karbing DS, Sølling CG, Winding RR, et al · · 2023 · cited 5× · PMID 37117014 · DOI 10.4187/respcare.10850