Who is sponsoring NCT05665010?

NCT05665010 is sponsored by Tongji Hospital.

What drugs are being tested in NCT05665010?

Interventions in NCT05665010: Genetic susceptibility.

What condition does NCT05665010 study?

NCT05665010 studies Premature Ovarian Insufficiency, Diminished Ovarian Reserve, Early Menopause.

Is NCT05665010 still recruiting?

NCT05665010 is currently status unknown. Last updated 27 December 2022.

Last reviewed 2022-12-27 · How we verify

NCT05665010

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Precise Stratification of Genetic Risk of Ovarian Function Impairment

Status unknown Last updated 27 December 2022

What this trial tests

trial testing Genetic susceptibility in Premature Ovarian Insufficiency in 1,000 participants. Status unknown.

Timeline

1 November 2021

Primary endpoint
31 October 2023

31 October 2024

Quick facts

Lead sponsor	Tongji Hospital
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	1,000
Start date	1 November 2021
Primary completion	31 October 2023
Estimated completion	31 October 2024
Sites	18 locations across China

Drugs / interventions tested

Genetic susceptibility

Conditions studied

Premature Ovarian Insufficiency — all drugs for Premature Ovarian Insufficiency →
Diminished Ovarian Reserve — all drugs for Diminished Ovarian Reserve →
Early Menopause — all drugs for Early Menopause →

Sponsor

Tongji Hospital

Who can join

Adults 18 to 40, female only, with Premature Ovarian Insufficiency or Diminished Ovarian Reserve. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Aging is a common problem in human society at present. The fertility decline, perimenopausal symptoms and senile diseases caused by ovarian aging seriously affect women's own health, offspring's health, family and social stability, and endanger national population security. Accurate stratification of genetic risk of ovarian aging has practical significance. Early and accurate identification of high-risk groups of premature ovarian aging can help such women to start early protection of ovarian function, preserve fertility to a greater extent, improve fertility quality, and also be conducive to early prevention and treatment of other systemic diseases and prognosis.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Association of LHCGR rs2293275 genotype with ovarian aging in Chinese women: a multicenter population-based study.
Ma W, Ye S, Tian L, Liu M, et al · · 2025 · cited 1× · PMID 40089715 · DOI 10.1186/s12958-025-01375-2

Verify or expand the search:

Other recruiting trials for Premature Ovarian Insufficiency

Currently open trials in the same condition.

NCT07510139 — A Clinical Study of Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes for the Treatment of Premature Ovarian Insuffi · Phase 1, PHASE2 · active not recruiting
NCT06851754 — Hormone Replacement Therapy in Adolescents With Premature Ovarian Insufficiency · Phase 3 · recruiting
NCT07275671 — Microbiome and Premature Ovarian Insufficiency · recruiting
NCT06645379 — Application of Platelet-rich Plasma (PRP) in Reproductive Medicine · NA · recruiting
NCT06481969 — Application of Autologous Adipose Stromal Vascular Fraction in the Treatment of Premature Ovarian Insufficiency · NA · recruiting

Other Tongji Hospital trials

Trials by the same sponsor.

NCT07537946 — Local Consolidation After Sintilimab Plus Lenvatinib for Metastatic Liver Cancer · Phase 3 · not yet recruiting
NCT07537972 — Denosumab Strategy for Liver Cancer With Bone Metastases · Phase 2 · not yet recruiting
NCT07537959 — Surgery Plus Systemic Therapy for Liver Cancer With Extrahepatic Metastases · NA · not yet recruiting
NCT07527260 — Effects of Adenoidectomy on Symptoms and IgE Levels in Children With AR · NA · not yet recruiting
NCT07524712 — Effects of Energy Versus Mechanical Surgical Devices on Postoperative Cough · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05665010 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Tongji Hospital
Last refreshed: 27 December 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05665010.

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