Last reviewed · How we verify
NCT05660733: Repia
Study of the Aortic and Large Arterial Vessel Infections
trial in Aortic Infections and Inflammations in 500 participants. Currently enrolling.
1 January 2027
Quick facts
| Lead sponsor | Central Hospital, Nancy, France |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 500 |
| Start date | 30 June 2023 |
| Primary completion | 1 January 2027 |
| Estimated completion | 1 January 2027 |
| Sites | 1 location across France |
Conditions studied
- Aortic Infections and Inflammations — all drugs for Aortic Infections and Inflammations →
- Mycotic Aneurysm — all drugs for Mycotic Aneurysm →
- Arterial Infections and Inflammations — all drugs for Arterial Infections and Inflammations →
- Prosthetic Infection — all drugs for Prosthetic Infection →
Sponsor
Central Hospital, Nancy, France
Who can join
18 and older, any sex, with Aortic Infections and Inflammations or Mycotic Aneurysm. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Aortic or large arterial vessel infections are rare but serious infections. Their management is based on French and American expert opinions. The quality of evidence supporting these guidelines is low because most publications on the subject correspond to case series and few interventional studies have been performed to validate their management. However, referral centres for vascular surgery are frequently solicited to give their opinion on patients suffering from mycotic aneurysms. In addition, the last few decades have seen the improvement of vascular surgery techniques allowing the management of more and more patients, often elderly and comorbid. There has therefore been an increase in the incidence of infectious complications associated with this care. It is therefore essential to participate in research on aortic and large arterial vessel infections. For this, a monocentric cohort study seems to be an essential first step to better understand the polymorphism and complexity of these patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Characteristics and outcomes of patients with infective native aortic aneurysm or vascular graft and endograft infection.
Lalevée L, Sergueï M, Jeanbert E, Simon M, et al · · 2025 · cited 1× · PMID 40377031 · DOI 10.1080/23744235.2025.2502826
Verify or expand the search:
- PubMed search for NCT05660733
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05660733 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Central Hospital, Nancy, France
- Last refreshed: 8 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05660733.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing