Who is sponsoring NCT05655260?

NCT05655260 is sponsored by University of Helsinki.

What drugs are being tested in NCT05655260?

Interventions in NCT05655260: Comparison of chemotherapy vs. chemoradiotherapy, Comparison of VBT vs. WPRT.

What condition does NCT05655260 study?

NCT05655260 studies Endometrial Adenocarcinoma.

Is NCT05655260 still recruiting?

NCT05655260 is currently recruiting now. Last updated 6 December 2024.

Last reviewed 2024-12-06 · How we verify

NCT05655260: PETREC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

PErsonalized TReatment for Endometrial Carcinoma

Recruiting now NA Last updated 6 December 2024

What this trial tests

NA trial testing Comparison of chemotherapy vs. chemoradiotherapy in Endometrial Adenocarcinoma in 300 participants. Currently enrolling.

Timeline

8 February 2022

Primary endpoint
31 December 2028

31 December 2028

Quick facts

Lead sponsor	University of Helsinki
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	300
Start date	8 February 2022
Primary completion	31 December 2028
Estimated completion	31 December 2028
Sites	1 location across Finland

Drugs / interventions tested

Comparison of chemotherapy vs. chemoradiotherapy
Comparison of VBT vs. WPRT

Conditions studied

Endometrial Adenocarcinoma — all drugs for Endometrial Adenocarcinoma →

Sponsor

University of Helsinki

Who can join

Adults 18 to 100, female only, with Endometrial Adenocarcinoma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this clinical trial is to compare the efficacy of adjuvant therapies in women with stage I-II molecular integrated high-intermediate or high-risk endometrial carcinoma. Specifically, the invesigators want to compare: * Chemotherapy vs. chemoradiotherapy in p53 abn subtype and nonendometrioid carcinomas. * Vaginal brachytherapy vs. whole pelvic radiotherapy in the MMR-D molecular subgroup. * Vaginal brachytherapy vs. whole pelvic radiotherapy in the NSMP molecular subgroup.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

PErsonalized TReatment for Endometrial Carcinoma (PETREC): study design and methods of a prospective Finnish multicenter trial.
Loukovaara M, Bützow R, Staff S, Mäenpää M, et al · · 2023 · cited 6× · PMID 37813479 · DOI 10.1136/ijgc-2023-004939
Unsolved Issues in the Integrated Histo-Molecular Classification of Endometrial Carcinoma and Therapeutic Implications.
Kuhn E, Gambini D, Runza L, Ferrero S, et al · · 2024 · cited 4× · PMID 39001520 · DOI 10.3390/cancers16132458

Verify or expand the search:

Other recruiting trials for Endometrial Adenocarcinoma

Currently open trials in the same condition.

NCT07077876 — Surgical and Obstetric Outcomes in Endometrial Adenocarcinoma and Atypical Endometrial Hyperplasia With Conservative Tre · recruiting
NCT06917092 — QL1706-Based Therapy Post-PD-1/L1 Failure in Advanced Endometrial Cancer · Phase 2 · recruiting
NCT05824481 — Study of Cadonilimab (AK104) Plus Lenvatinib in Patients With Advanced Endometrial Cancer · Phase 2 · active not recruiting
NCT05548296 — A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma · Phase 2 · recruiting
NCT05112601 — Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma · Phase 2 · recruiting

Other University of Helsinki trials

Trials by the same sponsor.

NCT07212361 — Infant Microbiota Restoration With Maternal Microbes · NA · recruiting
NCT06799988 — NutFinForce: The Impact of Digitally Delivered Lifestyle Performance Medicine Intervention on Defense Performance in Fin · not yet recruiting
NCT06464003 — Orthodontic Screening in Public Healthcare · recruiting
NCT06092372 — The Role of Genetics in Weight Loss · NA · completed
NCT06564675 — Accuracy of EEG Slow Wave Activity in Predicting Favourable Outcome in Patients With Hypoxic Brain Injury - A Substudy o · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05655260 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Helsinki
Last refreshed: 6 December 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05655260.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing