Who is sponsoring NCT05653947?

NCT05653947 is sponsored by Cairo University.

What drugs are being tested in NCT05653947?

Interventions in NCT05653947: Root canal instrumentation, 2.5% NaOCl irrigation.

What condition does NCT05653947 study?

NCT05653947 studies Apical Periodontitis.

Is NCT05653947 still recruiting?

NCT05653947 is currently completed. Last updated 19 January 2023.

Last reviewed 2023-01-19 · How we verify

NCT05653947

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Expression of IL-8 Before and After Root Canal Treatment in Patients With Symptomatic Apical Periodontitis

Completed NA Last updated 19 January 2023

What this trial tests

NA trial testing Root canal instrumentation, 2.5% NaOCl irrigation in Apical Periodontitis in 36 participants. Completed in 25 November 2022.

Timeline

10 March 2022

Primary endpoint
30 July 2022

25 November 2022

Quick facts

Lead sponsor	Cairo University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	screening
Enrollment	36
Start date	10 March 2022
Primary completion	30 July 2022
Estimated completion	25 November 2022
Sites	1 location across Egypt

Drugs / interventions tested

Root canal instrumentation, 2.5% NaOCl irrigation

Conditions studied

Apical Periodontitis — all drugs for Apical Periodontitis →

Sponsor

Cairo University

Who can join

Adults 20 to 50, any sex, with Apical Periodontitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This clinical study aimed to Compare the levels of Interleukin 8 before and after root canal treatment in patients with apical periodontitis * Diagnosis * Local anesthesia * Isolation and disinfection of the tooth * Two-staged access cavity preparation * Patency of the root canals * First sample collection using paper points * Working length determination * Chemico-mechanical preparation * After 1 week, isolation, Second sample collection then obturation of the root canals and restoration of the tooth. * Samples will be stored in (-80 C) freezer till collection of all samples then, quantification will be done using ELISA.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Apical Periodontitis

Currently open trials in the same condition.

NCT07237620 — The Effect of Different Intracanal Medicaments on Periapical Lesion Healing · NA · recruiting
NCT07307807 — Evaluation of Postoperative Pain and Lesion Healing in Periapical Lesion-Affected Teeth Obturated With Different Root Ca · NA · active not recruiting
NCT06843525 — Bite Force Measurements · recruiting
NCT07048028 — Chitosan Irrigation in Premolar Root Canal Therapy (Randomized Trial) · NA · recruiting
NCT07448571 — Evaluation of Revitalization Success Using i-PRF in Non-Surgical Root Canal Retreatment · NA · recruiting

Other Cairo University trials

Trials by the same sponsor.

NCT04155528 — Effect of Music Therapy on Postoperative Health Outcomes · NA · not yet recruiting
NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05653947 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cairo University
Last refreshed: 19 January 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05653947.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing